Featured Research

from universities, journals, and other organizations

Chronic smoking can diminish postural stability

Date:
April 8, 2014
Source:
Alcoholism: Clinical & Experimental Research
Summary:
Chronic cigarette smoking has a high co-occurrence with alcohol use disorders. Postural instability is also common among alcohol dependent individuals. New findings indicate that chronic cigarette use continues to impact the brain systems regulating postural stability even during abstinence from alcohol.

Chronic cigarette smoking has a high co-occurrence with alcohol use disorders, and roughly 60 to 90 percent of alcohol dependent (AD) individuals seeking treatment are chronic smokers. Postural instability is also common among AD individuals, because of damage to the brain systems that maintain postural stability. A new study of the effects of chronic cigarette smoking on postural stability has found that chronic cigarette use continues to impact the systems regulating postural stability even during abstinence.

Related Articles


Results will be published in the June 2014 online-only issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View.

"Based on both anecdotal and empirical findings, postural instabilities with eyes open or closed appear to be highly prevalent in treatment-seeking AD individuals," explained Thomas Paul Schmidt, a research associate in the department of radiology and biomedical imaging at the University of California San Francisco, and San Francisco Veterans Affairs Medical Center. "Other investigators looking at the relationships between falls and alcohol intake have also reported on increased fall risk in those with a history of problem drinking."

Schmidt, the corresponding author for the study, noted the uniqueness of its design. "Assessing postural stability over an eight-month period of abstinence from alcohol is not an easy feat considering relapse rates hover around 60 percent," he said. "In addition, we took into account the potentially harmful effects of concurrent cigarette smoking during abstinence from alcohol. This study is also the first to examine the effects of cigarette smoking on balance in non-alcohol dependent healthy controls."

"Public health initiatives focusing on the effects of chronic smoking have focused primarily on the negative effects on key organ systems such as those related to pulmonary function," added Sara Jo Nixon, a professor in the department of psychiatry at the University of Florida. "The current research reinforces findings from a growing literature reflecting its negative effects on neurobehavioral functions, suggesting that the common comorbidity of chronic smoking and AD may amplify the negative impact of either condition when considered separately."

Schmidt and his colleagues recruited AD study participants from substance-abuse outpatient clinics and controls from the local community. To assess postural stability and balance, an ataxia battery was administered to 115 smoking and non-smoking AD individuals and to 74 smoking and non-smoking light/non-drinking controls. Subgroups of AD individuals were assessed at three testing sessions during abstinence from alcohol: one week, five weeks, and 34 weeks of abstinence. All controls were assessed once, and a subset of the non-smoking controls was re-tested after 40 weeks. Using this data, study authors tested if cigarette smoking affected postural stability in both the control and AD groups, and if smoking influenced changes of postural stability during alcohol abstinence.

"One of our key findings was that non-smoking AD individuals improved significantly on a measure of postural stability over the course of eight months of sobriety," said Schmidt. "Smoking AD individuals exhibited no significant improvement across a similar time interval. This suggests that the neural and perceptual mechanisms responsible for postural stability are impacted by smoking, and even after chronic alcohol consumption has ceased. This finding is important for clinical treatment providers, because smoking is exceedingly common in AD individuals and during recovery from alcohol dependence."

"Brain systems underlying postural stability are known to be particularly sensitive to alcohol's neurotoxic effects," added Nixon. "The current work suggests that these areas may also be exquisitely sensitive to chronic smoking."

"The exact reason for why performance correlated with smoking severity but not with drinking measures is unclear," explained Schmidt. "There may be a biological reason, in that the correlation between smoking and postural stability is simply stronger than between alcohol consumption and postural stability. A more methodological reason may be that our smoking severity measures -- for example, number of cigarettes smoked per day -- are simply more accurate to quantify for our study participants than our measures of drinking severity -- such as average drinks consumed per month in the past year. It is easier for an AD individual to determine how many cigarettes they smoked on a typical day -- you just need to look how many cigarettes are left in that pack -- and then extrapolate back over the last years than to recall how many alcoholic drinks they consumed over the past year or even lifetime."

Despite questions that may remain about measures, Schmidt emphasized that smoking, chronic alcohol consumption, or a combination of the two can create severe health complications. "Many of these are relatively well known -- liver damage, lung cancer, respiratory problem," he said. "Yet research is also continually unearthing new and drastic ways in which smoking and drinking can affect your brain. More and more research now addresses how severely the brain and its functions are affected by both excessive drinking and smoking. For example, associations between smoking and risk for Alzheimer's disease are currently being studied."

Nixon agreed. "The negative effects of chronic smoking are not limited to those associated with cardiopulmonary disease or other well-recognized outcomes," she said. "They are also associated with subtle but significant compromise in fundamental brain function. Systematic work is needed to identify the breadth of these deficits, the process(es) of recovery, and individual differences in susceptibility. Given the high rates of smoking among individuals with substance use disorders, this population should be the focus of additional programmatic work."

"We hope that our findings will encourage more treatment providers to consider concurrent smoking cessation treatment within the greater context of treatment for AD," said Schmidt. "We also hope that individuals in treatment may consider smoking cessation as an aide for facilitating a more speedy recovery."


Story Source:

The above story is based on materials provided by Alcoholism: Clinical & Experimental Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. Thomas P. Schmidt, David L. Pennington, Timothy C. Durazzo, Dieter J. Meyerhoff. Postural Stability in Cigarette Smokers and During Abstinence from Alcohol. Alcoholism: Clinical and Experimental Research, 2014; DOI: 10.1111/acer.12409

Cite This Page:

Alcoholism: Clinical & Experimental Research. "Chronic smoking can diminish postural stability." ScienceDaily. ScienceDaily, 8 April 2014. <www.sciencedaily.com/releases/2014/04/140408162222.htm>.
Alcoholism: Clinical & Experimental Research. (2014, April 8). Chronic smoking can diminish postural stability. ScienceDaily. Retrieved November 29, 2014 from www.sciencedaily.com/releases/2014/04/140408162222.htm
Alcoholism: Clinical & Experimental Research. "Chronic smoking can diminish postural stability." ScienceDaily. www.sciencedaily.com/releases/2014/04/140408162222.htm (accessed November 29, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, November 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Tryptophan Isn't Making You Sleepy On Thanksgiving

Tryptophan Isn't Making You Sleepy On Thanksgiving

Newsy (Nov. 27, 2014) — Tryptophan, a chemical found naturally in turkey meat, gets blamed for sleepiness after Thanksgiving meals. But science points to other culprits. Video provided by Newsy
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) — Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) — Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins