Featured Research

from universities, journals, and other organizations

Recurrence of prostate cancer is significantly lower in men with blood group O

Date:
April 14, 2014
Source:
European Association of Urology
Summary:
A man’s blood group can affect the chance of a recurrence of prostate cancer after surgery, according to new research. This is the first time that this relationship has been demonstrated.Specifically, this new study has shown that patients with blood group O had a significantly decreased risk of cancer recurrence after radical prostatectomy.

A man's blood group can affect the chance of a recurrence of prostate cancer after surgery, according to new research, which was presented at the European Association of Urology congress in Stockholm. This is the first time that this relationship has been demonstrated.

Prostate cancer is the most common cancer in men, with huge differences in incidence across Europe. For localized prostate cancer the current "gold standard" treatment is Radical Prostatectomy (RP). However despite apparently successful surgery, approximately 30% of patients experience biochemical recurrence (shown by a rising level of Prostate Specific Antigen, PSA) during long-term follow-up.

This new study, from a team led by Dr Yoshio Ohno of Tokyo Medical University, has shown that patients with blood group O had a significantly decreased risk of cancer recurrence after radical prostatectomy (RP).

The team looked at 555 patients with localized prostate cancer who underwent RP between 2004 and 2010. After following the patients for an average of 52 months, they found that patients with blood group O were 35% less likely to have a recurrence of prostate cancer than patient who had blood group A.

Dr Ohno commented: "This is the first time that anyone has shown that prostate cancer recurrence can vary with blood group. Of course we need bigger studies to confirm the effect and also to see what practical application the finding might have. For example, we know that there are wide racial and geographical variations in the distribution of the ABO blood groups, and we need to be sure that this effect is significant in other groups.

As yet, we don't know why the risks vary with blood group, but this work may guide us towards new avenues of molecular research on prostate cancer progression. We need to consider what these results means in practical, clinical terms. For example, should we be counselling people with certain blood groups that they have a greater or lesser chance of recurrence, and should these risk factors be built into decisions on treatment?"

In the past, variation in ABO blood groups have been found to be associated with different risk of developing certain cancers, such as gastric and pancreatic cancers, and recently it has also been shown that prostate cancer incidence varies with blood group2.

Commenting, EAU General Secretary, Professor Per-Anders Abrahamsson (Malmo) said: "This is an interesting first finding. There is great geographical variation the incidence of prostate cancer, so there are obviously strong genetic factors at play. Blood groups have already been shown to be associated with prostate cancer incidence, not it looks like they might be associated with treatment outcomes as well."


Story Source:

The above story is based on materials provided by European Association of Urology. Note: Materials may be edited for content and length.


Cite This Page:

European Association of Urology. "Recurrence of prostate cancer is significantly lower in men with blood group O." ScienceDaily. ScienceDaily, 14 April 2014. <www.sciencedaily.com/releases/2014/04/140414091907.htm>.
European Association of Urology. (2014, April 14). Recurrence of prostate cancer is significantly lower in men with blood group O. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2014/04/140414091907.htm
European Association of Urology. "Recurrence of prostate cancer is significantly lower in men with blood group O." ScienceDaily. www.sciencedaily.com/releases/2014/04/140414091907.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins