Featured Research

from universities, journals, and other organizations

IV hormone infusion could treat common cause of infertility in women

Date:
May 4, 2014
Source:
European Society of Endocrinology
Summary:
Researchers have succeeded in restoring hormones essential for fertility that are commonly lost in women who exercise intensively, according to research. Fertility depends on a range of reproductive hormones. In females, one of these, called luteinising hormone is released from the brain in short bursts every 1-2 hours. When women undergo strict exercise regimes and restrict their calorific intake, energy is diverted away from maintaining their reproductive system.

Researchers have succeeded in restoring hormones essential for fertility that are commonly lost in women who exercise intensively, according to research presented today. The work, by researchers from Imperial College London, is presented this week at the European Congress of Endocrinology in Wrocłow, Poland.

Fertility depends on a range of reproductive hormones. In females, one of these, called luteinising hormone is released from the brain in short bursts every 1-2 hours. When women undergo strict exercise regimes and restrict their calorific intake, energy is diverted away from maintaining their reproductive system. This can lead to lower amounts of LH being released by the brain, resulting in loss of periods. This condition known as hypothalamic amenorrhea (HA) affects 1 in 100 women and 1 in 10 professional female athletes.

Kisspeptin is a hormone responsible for initiating pulses of LH. Previous studies have shown that women who have mutations in the gene coding for kisspeptin do not start puberty normally and can be infertile. In this study, five women between the ages of 18 and 40 suffering from HA were given 8-hour intravenous infusions of either kisspeptin or a saline placebo on six different occasions.

Researchers gave them a different dose of kisspeptin on each visit. At intermediate doses, women who received kisspeptin infusions released more LH and experienced an average of three times more LH pulses within 8 hours than those who received the placebo.

"We've shown that in the short term, IV infusions of kisspeptin at certain doses can restore the pulses of LH that are essential for female fertility," said Dr Channa Jayasena from Imperial College London who is the first-author on the study. The group plans to perform a larger study to confirm their findings. "The long-term aim is to determine whether kisspeptin could be used to treat certain forms of female infertility. If this is viable, it could provide an attractive and possibly less costly alternative to IVF," said Dr Jayasena.


Story Source:

The above story is based on materials provided by European Society of Endocrinology. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Endocrinology. "IV hormone infusion could treat common cause of infertility in women." ScienceDaily. ScienceDaily, 4 May 2014. <www.sciencedaily.com/releases/2014/05/140504095316.htm>.
European Society of Endocrinology. (2014, May 4). IV hormone infusion could treat common cause of infertility in women. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2014/05/140504095316.htm
European Society of Endocrinology. "IV hormone infusion could treat common cause of infertility in women." ScienceDaily. www.sciencedaily.com/releases/2014/05/140504095316.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins