Featured Research

from universities, journals, and other organizations

Water caged in buckyballs: Work on 'spin isomer conversion' may enhance magnetic resonance imaging

Date:
May 20, 2014
Source:
American Institute of Physics
Summary:
A research team describes how water molecules 'caged' in fullerene spheres ('buckyballs') are providing a deeper insight into spin isomers -- varieties of a molecule that differ in their nuclear spin. The results of this work may one day help enhance the analytical and diagnostic power of nuclear magnetic resonance and magnetic resonance imaging.

Studies of the molecular structure of the water-endofullerene H2O@C60 may enhance laboratory nuclear magnetic resonance (NMR) and clinical magnetic resonance imaging (MRI).
Credit: S.Mamone/University of Southampton

In a new paper in the Journal of Chemical Physics, produced by AIP Publishing, a research team in the United Kingdom and the United States describes how water molecules "caged" in fullerene spheres ("buckyballs") are providing a deeper insight into spin isomers -- varieties of a molecule that differ in their nuclear spin. The results of this work may one day help enhance the analytical and diagnostic power of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI).

Related Articles


Water molecules can exist as one of two isomers depending on how the spins of their two hydrogen atoms are oriented: ortho, where the spins are parallel and have a spin number of 1, and para, where the spins are antiparallel and have a spin number of 0. Scientists believe that any given molecule can transform from ortho- into para- spin states and vice versa, a process known as nuclear spin conversion.

"Currently, mechanisms for this conversion are not completely understood, nor how long it takes the molecules to transform from one spin isomer to the other," said Salvatore Mamone, a post-doctoral physicist at the University of Southampton and lead author on the JCP paper. "To study this, we had to figure out how to reduce the strong intermolecular interactions that are responsible for aggregation and lower the rotational mobility of the water molecules."

The answer was to use chemical reactions to open a hole in fullerene (C60, also known as a buckyball) spheres, inject water molecules and then close the "cages" to form a complex referred to as H2O@C60. "At the end of this synthetic preparation nicknamed 'molecular surgery,' we find that 70 to 90 percent of the cages are filled, giving us a significant quantity of water molecules to examine," Mamone said. "Because the [water] molecules are kept separated by the cages, there is a large rotational freedom that makes observation of the ortho and para isomers possible."

In their experiment, the researchers quickly cooled the individual H2O@C60 samples from 50 Kelvin (minus 223 degrees Celsius) to 5 K (minus 268 degrees Celsius) and then monitored their NMR signal every few minutes over several days.

"As the observed NMR signal is proportional to the amount of ortho-water in the sample [para-water with its spin number of 0 is "NMR silent"], we can track the percentages of ortho and para isomers at any time and any temperature," Mamone explained. "At 50 K, we find that 75 percent of the water molecules are ortho, while at 5 K, they become almost 100 percent para. Therefore, we know that after the quick temperature jump, equilibrium is restored by conversion from ortho to para -- and we see that conversion in real time."

A surprising outcome of the experiment was that the researchers observed a second-order rate law in the kinetics of the spin conversion which proves that pairs of molecules have to interact for conversion to occur. "Previous studies have speculated that other nuclear spins can cause conversion but we found this not to be the case for H2O@C60," Mamone said.

Next up, the research team plans to study the roles of isomer concentrations and temperature in the conversion process, the conversion of para-water to ortho ("back conversion"), how to detect single ortho- and para-water molecules on surfaces, and spin isomers in other fullerene-caged molecules.

In addition to the University of Southampton, researchers from this paper are affliated with Columbia University and the University of Nottingham.


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Journal Reference:

  1. Salvatore Mamone, Maria Concistrι, Elisa Carignani, Benno Meier, Andrea Krachmalnicoff, Ole G. Johannessen, Xuegong Lei, Yongjun Li, Mark Denning, Marina Carravetta, Kelvin Goh, Anthony J. Horsewill, Richard J. Whitby and Malcolm H. Levitt. Nuclear spin conversion of water inside fullerene cages detected by low-temperature nuclear magnetic resonance. Journal of Chemical Physics, May 20, 2014 DOI: 10.1063/1.4873343

Cite This Page:

American Institute of Physics. "Water caged in buckyballs: Work on 'spin isomer conversion' may enhance magnetic resonance imaging." ScienceDaily. ScienceDaily, 20 May 2014. <www.sciencedaily.com/releases/2014/05/140520115932.htm>.
American Institute of Physics. (2014, May 20). Water caged in buckyballs: Work on 'spin isomer conversion' may enhance magnetic resonance imaging. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2014/05/140520115932.htm
American Institute of Physics. "Water caged in buckyballs: Work on 'spin isomer conversion' may enhance magnetic resonance imaging." ScienceDaily. www.sciencedaily.com/releases/2014/05/140520115932.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Amazon Complains U.S. Is Too Slow To Regulate Drones

Amazon Complains U.S. Is Too Slow To Regulate Drones

Newsy (Mar. 25, 2015) — Days after getting approval to test certain commercial drones, Amazon says the Federal Aviation Administration is dragging its feet on the matter. Video provided by Newsy
Powered by NewsLook.com
Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Reuters - Innovations Video Online (Mar. 25, 2015) — European researchers say our smartphone use offers scientists an ideal testing ground for human brain plasticity. Dr Ako Ghosh&apos;s team discovered that the brains and thumbs of smartphone users interact differently from those who use old-fashioned handsets. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
China Wants to Export Its Steel Problem

China Wants to Export Its Steel Problem

Reuters - Business Video Online (Mar. 25, 2015) — China is facing a crisis with a glut of steel and growing public anger over the pollution created by production. In a move to solve the problem, some steel mills are looking to relocate overseas. Jane Lanhee Lee reports. Video provided by Reuters
Powered by NewsLook.com
Robot Stays on Its Feet Despite Punishment

Robot Stays on Its Feet Despite Punishment

Reuters - Innovations Video Online (Mar. 24, 2015) — Robotic engineers have modelled a two-legged robot to be fast and agile like an ostrich. The design is more efficient and stable than bipedal robots built to move like humans, according to its creators who abuse the poor machine to test its skills. Ben Gruber has more. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins