Featured Research

from universities, journals, and other organizations

Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic

Date:
May 21, 2014
Source:
American Chemical Society
Summary:
To the relief of patients diagnosed with hepatitis C, the US Food and Drug Administration approved two new treatments late last year, and a few more are on the way. Now scientists are solving another side of the disease's problem: identifying the millions more who have the virus but don't know it -- and unwittingly pass it on. A new report describes a novel, scrapbook-inspired test that does just that.

Scientists have developed a novel paper-based, rapid diagnostic test for hepatitis C.
Credit: American Chemical Society

To the relief of patients diagnosed with hepatitis C, the U.S. Food and Drug Administration approved two new treatments late last year, and a few more are on the way. Now scientists are solving another side of the disease's problem: identifying the millions more who have the virus but don't know it -- and unwittingly pass it on. A report in the ACS journal Analytical Chemistry describes a novel, scrapbook-inspired test that does just that.

Related Articles


Xuan Mu, Zhi Zheng and colleagues point out that the hepatitis C virus (HCV), a blood-borne pathogen that can cause liver cirrhosis, cancer and even death, kills more people in the U.S. than HIV. It also infects an estimated 150 million people around the world. Although diagnostic tests exist, they require an initial screening and then a costly second test for confirmation. The extra office visits, money and time required for a definitive diagnosis means a lot of people simply can't or won't follow up. To make diagnosis more accessible, the researchers took advantage of the recent development of new, inexpensive paper-based medical technologies and applied it to HCV screening.

Taking a page from the popular scrapbooking pastime, the scientists used a flower-shaped metal paper cutter to punch out shapes from special paper for their diagnostic test. The method solves the problem of patterning the paper, made of nitrocellulose -- a highly flammable substance -- without using heat. They add antigens, antibodies and other chemicals to the paper to test patient samples. With one flower-shaped paper, they can conduct both HCV tests on a sample simultaneously in just minutes, instead of hours.

The authors acknowledge support from the National Scientific and Technological Major Project of China and the National Natural Science Foundation of China.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xuan Mu, Lin Zhang, Shaoying Chang, Wei Cui, Zhi Zheng. Multiplex Microfluidic Paper-based Immunoassay for the Diagnosis of Hepatitis C Virus Infection. Analytical Chemistry, 2014; 140513101712000 DOI: 10.1021/ac500247f

Cite This Page:

American Chemical Society. "Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic." ScienceDaily. ScienceDaily, 21 May 2014. <www.sciencedaily.com/releases/2014/05/140521133702.htm>.
American Chemical Society. (2014, May 21). Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic. ScienceDaily. Retrieved January 31, 2015 from www.sciencedaily.com/releases/2014/05/140521133702.htm
American Chemical Society. "Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic." ScienceDaily. www.sciencedaily.com/releases/2014/05/140521133702.htm (accessed January 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, January 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins