Featured Research

from universities, journals, and other organizations

Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic

Date:
May 21, 2014
Source:
American Chemical Society
Summary:
To the relief of patients diagnosed with hepatitis C, the US Food and Drug Administration approved two new treatments late last year, and a few more are on the way. Now scientists are solving another side of the disease's problem: identifying the millions more who have the virus but don't know it -- and unwittingly pass it on. A new report describes a novel, scrapbook-inspired test that does just that.

Scientists have developed a novel paper-based, rapid diagnostic test for hepatitis C.
Credit: American Chemical Society

To the relief of patients diagnosed with hepatitis C, the U.S. Food and Drug Administration approved two new treatments late last year, and a few more are on the way. Now scientists are solving another side of the disease's problem: identifying the millions more who have the virus but don't know it -- and unwittingly pass it on. A report in the ACS journal Analytical Chemistry describes a novel, scrapbook-inspired test that does just that.

Related Articles


Xuan Mu, Zhi Zheng and colleagues point out that the hepatitis C virus (HCV), a blood-borne pathogen that can cause liver cirrhosis, cancer and even death, kills more people in the U.S. than HIV. It also infects an estimated 150 million people around the world. Although diagnostic tests exist, they require an initial screening and then a costly second test for confirmation. The extra office visits, money and time required for a definitive diagnosis means a lot of people simply can't or won't follow up. To make diagnosis more accessible, the researchers took advantage of the recent development of new, inexpensive paper-based medical technologies and applied it to HCV screening.

Taking a page from the popular scrapbooking pastime, the scientists used a flower-shaped metal paper cutter to punch out shapes from special paper for their diagnostic test. The method solves the problem of patterning the paper, made of nitrocellulose -- a highly flammable substance -- without using heat. They add antigens, antibodies and other chemicals to the paper to test patient samples. With one flower-shaped paper, they can conduct both HCV tests on a sample simultaneously in just minutes, instead of hours.

The authors acknowledge support from the National Scientific and Technological Major Project of China and the National Natural Science Foundation of China.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xuan Mu, Lin Zhang, Shaoying Chang, Wei Cui, Zhi Zheng. Multiplex Microfluidic Paper-based Immunoassay for the Diagnosis of Hepatitis C Virus Infection. Analytical Chemistry, 2014; 140513101712000 DOI: 10.1021/ac500247f

Cite This Page:

American Chemical Society. "Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic." ScienceDaily. ScienceDaily, 21 May 2014. <www.sciencedaily.com/releases/2014/05/140521133702.htm>.
American Chemical Society. (2014, May 21). Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2014/05/140521133702.htm
American Chemical Society. "Paper-based diagnostics, made with a scrapbooking tool, could curb hepatitis C pandemic." ScienceDaily. www.sciencedaily.com/releases/2014/05/140521133702.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins