Featured Research

from universities, journals, and other organizations

'Healthy' component of red wine, resveratrol, causes pancreatic abnormalities in fetuses

Date:
June 2, 2014
Source:
Federation of American Societies for Experimental Biology
Summary:
Here's more evidence that pregnant women should be careful about what they eat and drink: A new research report shows that when taken during pregnancy, resveratrol supplements led to developmental abnormalities in the fetal pancreas. This study has direct relevance to human health--Resveratrol is widely used for its recognized health benefits, and is readily available over the counter.

Here's more evidence that pregnant women should be careful about what they eat and drink: A new research report appearing in the June 2014 issue of The FASEB Journal shows that when taken during pregnancy, resveratrol supplements led to developmental abnormalities in the fetal pancreas. This study has direct relevance to human health--Resveratrol is widely used for its recognized health benefits, and is readily available over the counter.

"The important message in this study is that women should be very careful about what they consume while pregnant, and they should not take supplements, like Resveratrol, without consulting with their doctors," said Kevin L. Grove, Ph.D., a researcher involved in the work from the Division of Diabetes, Obesity and Metabolism and the Division of Reproductive and Development Science at Oregon Health and Science University in Portland, Oregon. "What might be good for the mother may not be good for the baby."

To make this discovery, Grove and colleagues administered Resveratrol supplements every day throughout pregnancy to obese female macaque monkeys consuming a Western diet. A second group of obese monkeys were not given the supplement, and all comparisons were made against lean monkeys fed a healthy low fat diet. The animals were closely monitored for health complications and blood flow through the placenta was determined by ultra sound. The fetuses were analyzed for developmental abnormalities, and findings showed definitive evidence of pancreatic abnormalities.

"We've known for a long time that resveratrol is pharmacologically active, and we're just now really beginning to understand the pros and cons of consuming high concentrations of this substance," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "As we begin to establish a safety profile for resveratrol and other dietary supplements, findings like this should come as no surprise. There are always negative side effects when you eat, drink, take or do too much of anything."


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. V. H. J. Roberts, L. D. Pound, S. R. Thorn, M. B. Gillingham, K. L. Thornburg, J. E. Friedman, A. E. Frias, K. L. Grove. Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates. The FASEB Journal, 2014; DOI: 10.1096/fj.13-245472

Cite This Page:

Federation of American Societies for Experimental Biology. "'Healthy' component of red wine, resveratrol, causes pancreatic abnormalities in fetuses." ScienceDaily. ScienceDaily, 2 June 2014. <www.sciencedaily.com/releases/2014/06/140602104752.htm>.
Federation of American Societies for Experimental Biology. (2014, June 2). 'Healthy' component of red wine, resveratrol, causes pancreatic abnormalities in fetuses. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2014/06/140602104752.htm
Federation of American Societies for Experimental Biology. "'Healthy' component of red wine, resveratrol, causes pancreatic abnormalities in fetuses." ScienceDaily. www.sciencedaily.com/releases/2014/06/140602104752.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins