Featured Research

from universities, journals, and other organizations

Urgent need for multifactorial interventions to treat diabetes mellitus

Date:
June 3, 2014
Source:
Florida Atlantic University
Summary:
World renowned researchers emphasize the critical need for clinicians to aggressively utilize a multi-pronged approach to reducing the risk of complications and premature death from type 2 diabetes mellitus. Clinicians should consider adopting all approaches of proven benefit in screening and managing their patients, which include adjunctive drug therapies to therapeutic lifestyle changes to achieve sustained weight loss, increases in physical activity, lipid, blood pressure and glycemic control.

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University; Marc A. Pfeffer, M.D., Dzau professor of medicine at Harvard Medical School; John W. Newcomer, M.D., executive vice dean of FAU's College of Medicine and interim vice president for research at FAU; Paul S. Jellinger, M.D., affiliate professor at the University of Miami Miller School of Medicine; and Alan Garber, M.D., Ph.D., professor of medicine at Baylor, have published a commentary in the American Journal of Managed Care titled "Treatment of Diabetes Mellitus: The Urgent Need for Multifactorial Interventions." These researchers emphasize the critical need for clinicians to aggressively utilize a multi-pronged approach to reducing the risk of complications and premature death from type 2 diabetes mellitus.

"There is an emerging pandemic of type 2 diabetes that is related to the dramatic increase in obesity, fast becoming the leading avoidable cause of death worldwide," said Hennekens. "People with type 2 diabetes have twice the risk for premature death due to complications from kidney failure, stroke, heart failure, and blindness due to retinopathy."

The authors state that intensive glucose control -- a cornerstone of treatment for patients with diabetes -- is necessary, but not sufficient to achieve the maximum benefits in reducing complications and premature death. Clinicians should consider adopting all approaches of proven benefit in screening and managing their patients, which include adjunctive drug therapies to therapeutic lifestyle changes to achieve sustained weight loss, increases in physical activity, lipid, blood pressure and glycemic control.

According to National Center of Health Statistics data from a random sample of the U.S. population aged 20 years and older, 20 percent have metabolic syndrome -- a constellation of high blood pressure, obesity, insulin resistance, and high cholesterol. In those 50 years or older, 40 percent have metabolic syndrome, and their 10-year risk for a first coronary event is 16 to 18 percent.

The authors advise that evidence-based doses of statins, aspirin, ACE inhibitors or ARBs should be prescribed as adjuncts to therapeutic lifestyle changes in the aggressive management of diabetes.

"The adoption of therapeutic lifestyle changes, which include weight loss and increased physical activity would preclude the need for pharmacologic interventions for most people with type 2 diabetes," said Hennekens. "Unfortunately, in the U.S., many patients prefer the prescription of pills to the prescription of a healthier lifestyle."

U.S. adolescents today are already heavier, less physically active, smoke more, and have already developed type 2 diabetes at a higher rate than their parents' generation did in their adolescence. Thus, they may become the first U.S. generation since 1950 to have higher rates of cardiovascular disease than their parents.

From a clinical and public health perspective, the authors also express their concern on the alarming findings regarding the under-treatment of type 2 diabetes in sub-populations in the U.S. such as the mentally ill as well as in many countries worldwide. They provide best practices guidelines for blood pressure and cholesterol screenings, while urging clinicians and policy makers to implement multifactorial interventions.

It is estimated that if present trends in obesity and physical inactivity continue, it is likely that one-third of U.S. adults will have diabetes by 2050.


Story Source:

The above story is based on materials provided by Florida Atlantic University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Charles H. Hennekens, MD; Marc A. Pfeffer, MD; John W. Newcomer, MD; Paul S. Jellinger, MD, MACE; and Alan Garber, MD, PhD. Treatment of Diabetes Mellitus: The Urgent Need for Multifactorial Interventions. American Journal of Managed Care, May 2014

Cite This Page:

Florida Atlantic University. "Urgent need for multifactorial interventions to treat diabetes mellitus." ScienceDaily. ScienceDaily, 3 June 2014. <www.sciencedaily.com/releases/2014/06/140603091958.htm>.
Florida Atlantic University. (2014, June 3). Urgent need for multifactorial interventions to treat diabetes mellitus. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2014/06/140603091958.htm
Florida Atlantic University. "Urgent need for multifactorial interventions to treat diabetes mellitus." ScienceDaily. www.sciencedaily.com/releases/2014/06/140603091958.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Newsy (July 30, 2014) The Peace Corps is one of several U.S.-based organizations to pull workers out of West Africa because of the Ebola outbreak. Video provided by Newsy
Powered by NewsLook.com
Weather Kills 2K A Year, But Storms Aren't The Main Offender

Weather Kills 2K A Year, But Storms Aren't The Main Offender

Newsy (July 30, 2014) Health officials say 2,000 deaths occur each year in the U.S. due to weather, but it's excessive heat and cold that claim the most lives. Video provided by Newsy
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins