Featured Research

from universities, journals, and other organizations

Vitamin D deficiency linked to higher risk of cardiovascular, cancer death

Date:
June 30, 2014
Source:
Mount Sinai Medical Center
Summary:
Analysis of pooled data showed a strong association between low vitamin D levels and risk of death in general death from cardiovascular diseases, death in from cancer, at least in older people with a history of cancer. "Going into our study, the effect of vitamin D supplementation on risk of death was not clear," said the lead investigator. "Our analysis confirms the protective nature of this substance especially in elderly patients."

A vitamin D boost may prevent early death from heart disease and cancer, according to a large scale study by Mount Sinai and a consortium of international collaborators, published online in the June issue of BMJ. Analysis of pooled data by Paolo Boffetta, MD, Director of the Institute for Translational Epidemiology and Associate Director for Population Sciences of the Tisch Cancer Institute at Mount Sinai, and collaborators showed a strong association between low vitamin D levels and risk of death in general death from cardiovascular diseases, death in from cancer, at least in older people with a history of cancer.

Past studies have linked Vitamin D to protection against many health problems, including hypertension, diabetes and bone loss. Could its protective role be even greater? "Going into our study, the effect of vitamin D supplementation on risk of death was not clear," said Dr. Boffetta. "Our analysis confirms the protective nature of this substance especially in elderly patients."

The skin makes Vitamin D when exposed to sunlight, and we also take it in through dietary sources and supplements. Deficiency is most common in the elderly, who get less sun. Limited understanding of just how much Vitamin D is needed to achieve protection has meant a lack of consistent recommendations on supplementation, and the verdict is still out. The current study results argue that those deficient in Vitamin D are more likely to die before those who are not, says Dr. Boffetta.

Researchers analyzed data from eight European and American studies that included 26,018 men and women aged 50-79 years. Follow-up analysis showed that 6,695 study participants died during the studies, including 2,624 from cardiovascular diseases and 2,227 from cancer. Comparison of the lowest and the highest levels of Vitamin D in the deceased showed those with the lowest concentrations had a pooled risk ratio of 1.57, or nearly double the risk of overall death as those with high concentrations. Risk ratios for cardiovascular and cancer deaths in those with cancer history were similar. Despite varying levels of Vitamin D between country, sex and season of blood draw, the association between low levels of vitamin D and death was consistent.

"Vitamin D's protective effect is clear," says Dr. Boffetta. "If our results are confirmed in additional studies, it could lead to recommendations for greater Vitamin D supplementation in foods, and to a better understanding of its role in cancer prognosis."


Story Source:

The above story is based on materials provided by Mount Sinai Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. B. Schottker, R. Jorde, A. Peasey, B. Thorand, E. H. J. M. Jansen, L. d. Groot, M. Streppel, J. Gardiner, J. M. Ordonez-Mena, L. Perna, T. Wilsgaard, W. Rathmann, E. Feskens, E. Kampman, G. Siganos, I. Njolstad, E. B. Mathiesen, R. Kubinova, A. Pajk, R. Topor-Madry, A. Tamosiunas, M. Hughes, F. Kee, M. Bobak, A. Trichopoulou, P. Boffetta, H. Brenner. Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States. BMJ, 2014; 348 (jun17 16): g3656 DOI: 10.1136/bmj.g3656

Cite This Page:

Mount Sinai Medical Center. "Vitamin D deficiency linked to higher risk of cardiovascular, cancer death." ScienceDaily. ScienceDaily, 30 June 2014. <www.sciencedaily.com/releases/2014/06/140630113445.htm>.
Mount Sinai Medical Center. (2014, June 30). Vitamin D deficiency linked to higher risk of cardiovascular, cancer death. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2014/06/140630113445.htm
Mount Sinai Medical Center. "Vitamin D deficiency linked to higher risk of cardiovascular, cancer death." ScienceDaily. www.sciencedaily.com/releases/2014/06/140630113445.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: World's Oldest Man Lives in Japan

Raw: World's Oldest Man Lives in Japan

AP (Aug. 20, 2014) A 111-year-old Japanese was certified as the world's oldest man by Guinness World Records on Wednesday. Sakari Momoi, a native of Fukushima in northern Japan, was given a certificate at a hospital in Tokyo. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins