Featured Research

from universities, journals, and other organizations

Acetone in breath of Four Days Marches participants provides information on fat burning

Date:
July 9, 2014
Source:
Radboud University Nijmegen
Summary:
The concentration of acetone in breath is a suitable marker of fat burning during physical activity, physicists have shown for the first time. Their study, conducted on walkers taking part in the International Four Days Marches in Nijmegen, the Netherlands, shows that there are differences between healthy walkers and those suffering from diabetes.

Physicists at Radboud University Nijmegen have shown for the first time that the concentration of acetone in breath is a suitable marker of fat-burning during physical activity. Their study, conducted on walkers taking part in the International Four Days Marches in Nijmegen, the Netherlands, shows that there are differences between healthy walkers and those suffering from diabetes.

Related Articles


'When we exercise, our body first uses sugar from food as source of energy', explains Simona Cristescu, physicist at Radboud University Nijmegen and leader of the research project. 'In healthy people, the body will obtain the necessary energy by burning fat, if not enough sugar is available.' For people suffering from diabetes, insulin availability (in Type 1) or insulin sensitivity (in Type 2) is dictating the energy production, storage and use. During fat oxidation, breakdown products such as ketones are produced and can be found in urine and in exhaled breath (i.e. acetone). In conditions such as intense or prolonged exercising, their excess production can acidify the blood and this can be harmful. The concentration of acetone in a person's breath turns out to be a good indicator of the rate of fat-burning while keeping the body healthy.

Breath balloons Fifty one walkers taking part in the International Four Days Marches were asked to exhale into a 1 litre balloon twice a day, before starting and at the end of the walk. Acetone concentration in breath was tested within eight hours from collection with a mass spectrometer developed at the Trace Gas Facility, a laboratory at Radboud University Nijmegen that enables tiny amounts of a gas to be detected -- even few gas molecules amongst a thousand billion others. In the case of healthy walkers and, to an even greater extent, walkers with Type 1 diabetes, the amount of acetone in the breath increased during the walk. This was not the case, however, for walkers with Type 2 diabetes, as they take medicine that enables the body to use more sugar. The researchers verified their results by also testing the walkers' urine; the acetone concentrations measured showed comparable patterns.

Field conditions Apart from the required monitoring moments, the walkers did not have to follow any special rules: they could eat and drink whatever and whenever they liked, and the researchers did not have any control over the amount of sleep or any other activities, apart from the miles walked for the Four Days Marches. As Cristescu explains, the fact that the experiment was carried out in such a natural, uncontrolled setting makes the findings even stronger. 'Our ultimate goal is to develop a tool allowing people, with or without diabetes, to determine the acetone in their own breath easily and in real time. This will enable them to monitor the rate at which they are burning fat and, furthermore, to take action before blood acidification. They can then stop the physical activity at the point when it is doing more harm than good.'

The testing of International Four Days Marches participants was a collaborative project between physicists and physiologists at Radboud University and Radboudumc as part of an EFRO project, funded by the European Regional Development Fund and the province of Gelderland.


Story Source:

The above story is based on materials provided by Radboud University Nijmegen. Note: Materials may be edited for content and length.


Journal Reference:

  1. Devasena Samudrala, Gerwen Lammers, Julien Mandon, Lionel Blanchet, Tim H.A. Schreuder, Maria T. Hopman, Frans J.M. Harren, Luc Tappy, Simona M. Cristescu. Breath acetone to monitor life style interventions in field conditions: An exploratory study. Obesity, 2014; 22 (4): 980 DOI: 10.1002/oby.20696

Cite This Page:

Radboud University Nijmegen. "Acetone in breath of Four Days Marches participants provides information on fat burning." ScienceDaily. ScienceDaily, 9 July 2014. <www.sciencedaily.com/releases/2014/07/140709095501.htm>.
Radboud University Nijmegen. (2014, July 9). Acetone in breath of Four Days Marches participants provides information on fat burning. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2014/07/140709095501.htm
Radboud University Nijmegen. "Acetone in breath of Four Days Marches participants provides information on fat burning." ScienceDaily. www.sciencedaily.com/releases/2014/07/140709095501.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) — A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) — Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) — Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) — Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins