Featured Research

from universities, journals, and other organizations

Acetone in breath of Four Days Marches participants provides information on fat burning

Date:
July 9, 2014
Source:
Radboud University Nijmegen
Summary:
The concentration of acetone in breath is a suitable marker of fat burning during physical activity, physicists have shown for the first time. Their study, conducted on walkers taking part in the International Four Days Marches in Nijmegen, the Netherlands, shows that there are differences between healthy walkers and those suffering from diabetes.

Physicists at Radboud University Nijmegen have shown for the first time that the concentration of acetone in breath is a suitable marker of fat-burning during physical activity. Their study, conducted on walkers taking part in the International Four Days Marches in Nijmegen, the Netherlands, shows that there are differences between healthy walkers and those suffering from diabetes.

'When we exercise, our body first uses sugar from food as source of energy', explains Simona Cristescu, physicist at Radboud University Nijmegen and leader of the research project. 'In healthy people, the body will obtain the necessary energy by burning fat, if not enough sugar is available.' For people suffering from diabetes, insulin availability (in Type 1) or insulin sensitivity (in Type 2) is dictating the energy production, storage and use. During fat oxidation, breakdown products such as ketones are produced and can be found in urine and in exhaled breath (i.e. acetone). In conditions such as intense or prolonged exercising, their excess production can acidify the blood and this can be harmful. The concentration of acetone in a person's breath turns out to be a good indicator of the rate of fat-burning while keeping the body healthy.

Breath balloons Fifty one walkers taking part in the International Four Days Marches were asked to exhale into a 1 litre balloon twice a day, before starting and at the end of the walk. Acetone concentration in breath was tested within eight hours from collection with a mass spectrometer developed at the Trace Gas Facility, a laboratory at Radboud University Nijmegen that enables tiny amounts of a gas to be detected -- even few gas molecules amongst a thousand billion others. In the case of healthy walkers and, to an even greater extent, walkers with Type 1 diabetes, the amount of acetone in the breath increased during the walk. This was not the case, however, for walkers with Type 2 diabetes, as they take medicine that enables the body to use more sugar. The researchers verified their results by also testing the walkers' urine; the acetone concentrations measured showed comparable patterns.

Field conditions Apart from the required monitoring moments, the walkers did not have to follow any special rules: they could eat and drink whatever and whenever they liked, and the researchers did not have any control over the amount of sleep or any other activities, apart from the miles walked for the Four Days Marches. As Cristescu explains, the fact that the experiment was carried out in such a natural, uncontrolled setting makes the findings even stronger. 'Our ultimate goal is to develop a tool allowing people, with or without diabetes, to determine the acetone in their own breath easily and in real time. This will enable them to monitor the rate at which they are burning fat and, furthermore, to take action before blood acidification. They can then stop the physical activity at the point when it is doing more harm than good.'

The testing of International Four Days Marches participants was a collaborative project between physicists and physiologists at Radboud University and Radboudumc as part of an EFRO project, funded by the European Regional Development Fund and the province of Gelderland.


Story Source:

The above story is based on materials provided by Radboud University Nijmegen. Note: Materials may be edited for content and length.


Journal Reference:

  1. Devasena Samudrala, Gerwen Lammers, Julien Mandon, Lionel Blanchet, Tim H.A. Schreuder, Maria T. Hopman, Frans J.M. Harren, Luc Tappy, Simona M. Cristescu. Breath acetone to monitor life style interventions in field conditions: An exploratory study. Obesity, 2014; 22 (4): 980 DOI: 10.1002/oby.20696

Cite This Page:

Radboud University Nijmegen. "Acetone in breath of Four Days Marches participants provides information on fat burning." ScienceDaily. ScienceDaily, 9 July 2014. <www.sciencedaily.com/releases/2014/07/140709095501.htm>.
Radboud University Nijmegen. (2014, July 9). Acetone in breath of Four Days Marches participants provides information on fat burning. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2014/07/140709095501.htm
Radboud University Nijmegen. "Acetone in breath of Four Days Marches participants provides information on fat burning." ScienceDaily. www.sciencedaily.com/releases/2014/07/140709095501.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) — New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) — Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) — Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) — Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins