Featured Research

from universities, journals, and other organizations

Best anticoagulants after orthopedic procedures depends on type of surgery

Date:
July 17, 2014
Source:
Wiley
Summary:
Current guidelines do not distinguish between aspirin and more potent blood thinners for protecting against blood clots in patients who undergo major orthopedic operations, leaving the decision up to individual clinicians. A new analysis now provides much-needed information that summarizes existing studies about which medications are best after different types of surgery.

Current guidelines do not distinguish between aspirin and more potent blood thinners for protecting against blood clots in patients who undergo major orthopedic operations, leaving the decision up to individual clinicians. A new analysis published in the Journal of Hospital Medicine provides much-needed information that summarizes existing studies about which medications are best after different types of surgery.

Related Articles


Every year, hundreds of thousands of Americans undergo major orthopedic surgery such as hip and knee replacements and hip fracture repairs. Patients undergoing such operations are at risk of experiencing serious, potentially fatal blood clots. Attempts to prevent blood clots with medications that thin the blood can be problematic, though, because they can worsen bleeding, which is another serious complication after surgery. Indeed, there is considerable controversy concerning the best type of blood thinner to use: aspirin or stronger blood thinners called anticoagulants. Examples of anticoagulants include heparin and warfarin (Coumadin).

Researchers compiled and compared all relevant studies that have compared these agents following hip or knee surgery. Their analysis, which included 8 randomized trials and 1408 patients, revealed that for hip or knee replacement, aspirin may be a good option because it's as effective as heparin or warfarin for preventing blood clots, but with less risk of bleeding. After hip fracture repair, though, anticoagulation therapy appears to be more beneficial.

"We expect that the number of hip and knee replacements and hip fracture repairs will continue to grow as the population ages. Major complications after these procedures -- often clots or bleeding -- contribute to suffering and costs," said lead author Frank Drescher, MD of the Veterans Affairs Medical Center in White River Junction, Vermont. "We hope our findings may guide physicians trying to help their patients make decisions about how to best minimize surgical risks."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Frank S. Drescher, Brenda E. Sirovich, Alexandra Lee, Daniel H. Morrison, Wesley H. Chiang, Robin J. Larson. Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: A systematic review and meta-analysis. Journal of Hospital Medicine, 2014; DOI: 10.1002/jhm.2224

Cite This Page:

Wiley. "Best anticoagulants after orthopedic procedures depends on type of surgery." ScienceDaily. ScienceDaily, 17 July 2014. <www.sciencedaily.com/releases/2014/07/140717094816.htm>.
Wiley. (2014, July 17). Best anticoagulants after orthopedic procedures depends on type of surgery. ScienceDaily. Retrieved November 29, 2014 from www.sciencedaily.com/releases/2014/07/140717094816.htm
Wiley. "Best anticoagulants after orthopedic procedures depends on type of surgery." ScienceDaily. www.sciencedaily.com/releases/2014/07/140717094816.htm (accessed November 29, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins