Featured Research

from universities, journals, and other organizations

Brain benefits from weight loss following bariatric surgery

Date:
August 26, 2014
Source:
Endocrine Society
Summary:
Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study. Bariatric surgery is used to help people who are dangerously obese lose weight. Bariatric surgery procedures are designed to restrict the amount of food you can eat before you feel full by reducing the stomach's size or limit the absorption of nutrients by removing part of the small intestine from the path food takes through the digestive tract.

Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Obesity can tax the brain as well as other organs. Obese individuals face a 35 percent higher risk of developing Alzheimer's disease compared to normal weight people.

Bariatric surgery is used to help people who are dangerously obese lose weight. Bariatric surgery procedures are designed to restrict the amount of food you can eat before you feel full by reducing the stomach's size or limit the absorption of nutrients by removing part of the small intestine from the path food takes through the digestive tract. Some procedures, such as Roux-en-Y gastric bypass (RYBG) surgery, use a combination of these methods. This study was the first to assess brain activity in women before and after bariatric surgery.

"When we studied obese women prior to bariatric surgery, we found some areas of their brains metabolized sugars at a higher rate than normal weight women," said one of the study's authors, Cintia Cercato, MD, PhD, of the University of São Paolo in São Paolo, Brazil. "In particular, obesity led to altered activity in a part of the brain linked to the development of Alzheimer's disease -- the posterior cingulate gyrus. Since bariatric surgery reversed this activity, we suspect the procedure may contribute to a reduced risk of Alzheimer's disease and other forms of dementia."

The longitudinal study examined the effect of RYBG surgery on the brain function of 17 obese women. Researchers used positron emission tomography (PET) scans and neuropsychological tests to assess brain function and activity in the participants prior to surgery and six months after the procedure. The same tests also were run once on a control group of 16 lean women.

Before they underwent surgery, the obese women had higher rates of metabolism in certain areas of the brain, including the posterior cingulate gyrus. Following surgery, there was no evidence of this exacerbated brain activity. Their brain metabolism rates were comparable to the activity seen in normal weight women.

After surgery, the obese women also performed better on a test measuring executive function -- the brain's ability to connect past experience and present action -- than they did before the procedures. Executive function is used in planning, organizing and strategizing. Five other neuropsychological tests measuring various aspects of memory and cognitive function showed no change following the surgery.

"Our findings suggest the brain is another organ that benefits from weight loss induced by surgery," Cercato said. "The increased brain activity the obese women exhibited before undergoing surgery did not result in improved cognitive performance, which suggests obesity may force the brain to work harder to achieve the same level of cognition."


Story Source:

The above story is based on materials provided by Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cintia Cercato et al. Changes in Neuropsychological Tests and Brain Metabolism After Bariatric Surgery. Journal of Clinical Endocrinology & Metabolism, August 2014 DOI: 10.1210/jc.2014

Cite This Page:

Endocrine Society. "Brain benefits from weight loss following bariatric surgery." ScienceDaily. ScienceDaily, 26 August 2014. <www.sciencedaily.com/releases/2014/08/140826141128.htm>.
Endocrine Society. (2014, August 26). Brain benefits from weight loss following bariatric surgery. ScienceDaily. Retrieved September 14, 2014 from www.sciencedaily.com/releases/2014/08/140826141128.htm
Endocrine Society. "Brain benefits from weight loss following bariatric surgery." ScienceDaily. www.sciencedaily.com/releases/2014/08/140826141128.htm (accessed September 14, 2014).

Share This



More Health & Medicine News

Sunday, September 14, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Contagious Respiratory Illness Continues to Spread Across U.S.

Contagious Respiratory Illness Continues to Spread Across U.S.

Reuters - US Online Video (Sep. 12, 2014) — Hundreds of children in several states have been stricken by a serious respiratory illness that is spreading across the U.S. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Batters Sierra Leone Economy Too

Ebola Batters Sierra Leone Economy Too

Reuters - Business Video Online (Sep. 12, 2014) — The World Health Organisation warns that local health workers in West Africa can't keep up with Ebola - and among those countries hardest hit by the outbreak, the economic damage is coming into focus, too. As David Pollard reports, Sierra Leone admits that growth in one of the poorest economies in the region is taking a beating. Video provided by Reuters
Powered by NewsLook.com
Health Care Workers 'Chasing' Ebola Outbreak

Health Care Workers 'Chasing' Ebola Outbreak

Newsy (Sep. 12, 2014) — The worst known Ebola outbreak is proving extremely difficult to contain. Hospitals are full, and victims of the virus are suffering in the streets. Video provided by Newsy
Powered by NewsLook.com
Ebola Sparks Economic Contagion

Ebola Sparks Economic Contagion

Reuters - Business Video Online (Sep. 11, 2014) — African countries with Ebola are suffering financially. But as Sonia Legg reports, there are now signs that economic contagion is starting to spread to other parts of the continent - even those miles from the outbreak. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins