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Concerns about industry dominance in diabetes research

Date:
July 1, 2015
Source:
BMJ
Summary:
Diabetes research is dominated by a small group of prolific authors, raising questions about the imbalance of power and conflict of interests in this field, argue experts in a new article.
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Diabetes research is dominated by a small group of prolific authors, raising questions about the imbalance of power and conflict of interests in this field, argue experts in The BMJ.

In a new study, Frits Holleman and colleagues searched PubMed for all randomised controlled studies (RCTs) on glucose lowering treatments for diabetes from 1993 to 2013.

In total, they identified 3,782 articles with 13,592 authors.

The top 110 authors were named in a third (32.4%) of all articles, and they authored 991 RCTs, equivalent to 20 RCTs per author.

Of these 110 authors, 44% were employed by pharmaceutical companies and 56% were academics who worked closely with the industry. And of the 991 RCTs, 906 were commercially sponsored.

More than 80% of the top 110 authors came from four countries -- the USA, Italy, the UK or Germany.

A group of 11 authors, referred to as 'supertrialists', contributed to 397 (10%) of all articles, including 354 RCTs, equivalent to 42 publications each.

Overall, 704 articles could be assessed for conflicts of interest, and only 42 (6%) were considered fully independent. In articles with at least one pharmaceutical author, 89% of the co-authors had a conflict of interest.

The authors of the study write that the evidence base for diabetes might suffer from a small number of "truly independent research and an over-reliance of the diabetes community on a few authors from a few countries who have substantial conflicts of interest."

They argue that authorship should be distributed more fairly and call on journals to provide more detail on the individual contribution of authors in line with recommendations from The International Committee of Medical Journal Editors.

In a linked editorial, Elizabeth Wager argues that this study highlights "a serious imbalance of power" and calls for a "change of institutional culture" to reward quality of research over quantity of articles. She also calls for a "radical overhaul" of authorship guidelines for a new system that reflects current research practices.


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Materials provided by BMJ. Note: Content may be edited for style and length.


Journal Reference:

  1. Frits Holleman et al. Productivity of authors in the field of diabetes: bibliographic analysis of trial publications. The BMJ, July 2015 DOI: 10.1136/bmj.h2638

Cite This Page:

BMJ. "Concerns about industry dominance in diabetes research." ScienceDaily. ScienceDaily, 1 July 2015. <www.sciencedaily.com/releases/2015/07/150701214541.htm>.
BMJ. (2015, July 1). Concerns about industry dominance in diabetes research. ScienceDaily. Retrieved May 24, 2017 from www.sciencedaily.com/releases/2015/07/150701214541.htm
BMJ. "Concerns about industry dominance in diabetes research." ScienceDaily. www.sciencedaily.com/releases/2015/07/150701214541.htm (accessed May 24, 2017).

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