Pharmaceuticals News

July 26, 2024

Top Headlines

Dual Action Antibiotic Could Make Bacterial Resistance Nearly Impossible

July 23, 2024 — New drug that disrupts two cellular targets would make it much harder for bacteria to evolve ...

Team Marks Milestone in Progress Toward Investigational New Drug for Triple-Negative Breast Cancer

July 22, 2024 — A new compound shows promise in overcoming chemotherapy resistance in triple-negative breast cancer -- and could potentially be applied to fibrotic conditions like liver fibrosis or pulmonary ...

Enzyme-Powered 'Snot Bots' Help Deliver Drugs in Sticky Situations

July 17, 2024 — Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues -- it also lines and helps protect the lungs, stomach, intestines and eyes. ...

E. Coli Variant May Cause Antimicrobial Resistance in Dogs, Humans

July 16, 2024 — Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ...

Latest Headlines

updated 9:42pm EDT

Combination Treatment Based on Drug Repurposing Shows Promise in the Treatment of Retinal Degenerations

July 22, 2024 — Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study. A combination treatment incorporating three ...

Diabetes Drug Reduces Drug Resistance in Lung Cancer, Improving Chemotherapy Effectiveness

July 17, 2024 — A medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according to new ...

Unlocking the Mystery of Preexisting Drug Resistance: New Study Sheds Light on Cancer Evolution

July 15, 2024 — The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that ...

New Research Demonstrates Potential for Increasing Effectiveness of Popular Diabetes, Weight-Loss Drugs

July 15, 2024 — A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of popular ...

A Comprehensive Derivative Synthesis Method for Development of New Antimicrobial Drugs

July 11, 2024 — A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant ...

Novel Compound Offers Improved Defense Against Fentanyl Overdoses

July 8, 2024 — Researchers identified a novel compound aimed at improving the treatment of opioid ...

Re-Engineering Cancerous Tumors to Self-Destruct and Kill Drug-Resistant Cells

July 4, 2024 — Researchers have found a way to reprogram disease evolution and design tumors that are easier to treat. They created a modular genetic circuit that ...

New Study Shows Medication Abortion Without Ultrasound to Be Safe

June 24, 2024 — Medication abortion patients who receive pills by mail without first getting an ultrasound do just as well as those who are examined and given the drugs in person, new research has ...

Treatment With a Mixture of Antimicrobial Peptides Can Impede Antibiotic Resistance

July 2, 2024 — A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather ...

Chemists Synthesize an Improved Building Block for Medicines

July 3, 2024 — Research could help drug developers improve the safety profiles of medications and reduce side ...

Using Visible Light to Make Pharmaceutical Building Blocks

July 2, 2024 — Chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals. The class of compounds, called azetidines, had been ...

Breakthrough Research Makes Cancer-Fighting Viral Agent More Effective

June 28, 2024 — Researchers have made a significant breakthrough by discovering that the drug 4-OI can enhance the effectiveness of a cancer-fighting viral agent. This may lead to treatment of cancers that are ...

Intriguing New Tool for Tendon Healing: Nanoparticles for Precision Drug Delivery

June 27, 2024 — Harnessing nanoparticles to deliver drugs precisely to a surgically repaired tendon is a promising new approach that reduced scar tissue formation and improved mechanical ...

Could Preventative Drug Be Effective in People With Migraine and Rebound Headache?

June 26, 2024 — A drug used to prevent migraine may also be effective in people with migraine who experience rebound headaches, according to a new ...

Your Future Medications Could Be Personalized for You on a 3D Printer

June 25, 2024 — Scientists are helping to develop standards and safety protocols that would allow pharmacies to print drugs onsite at a dosage best for ...

New Study Demonstrates the Efficacy of a Promising Celiac Disease Drug at the Molecular Level

June 24, 2024 — A recent study investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease. Previous tissue studies have shown that the ZED1227 transglutaminase 2 inhibitor ...

Study Reveals New Opportunities to Develop Cancer Treatments

June 24, 2024 — Researchers uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this ...

Trial Offers Hope for Cheaper, More Tolerable, Ketamine Treatment

June 24, 2024 — For those suffering from treatment-resistant depression, the anaesthetic drug ketamine offers hope, but it has side effects and can be costly to access -- a clinical trial may change ...

Study Identifies First Drug Therapy for Sleep Apnea

June 21, 2024 — An international study shows new drug improves sleep, health in patients diagnosed with obesity and sleep ...

Membrane Protein Analogues Could Accelerate Drug Discovery

June 21, 2024 — Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

A New Method for Improving Checkpoint Inhibitor Therapy for Cancer

June 20, 2024 — Research scientists found that a 'one-two punch' of combining the immunosuppressive drug ruxolitinib with existing checkpoint inhibitor therapies may be a more effective way to fight some ...

Mirror-Image Chemicals May Revolutionize Drug Delivery

June 18, 2024 — More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery ...

Promising Approach to Prevent Recurrence of Breast Cancer

June 17, 2024 — Treatment outcomes for breast cancer have become better over the years, but proportion of breast cancers still recur even after long periods without signs of cancer remaining dormant in the body. ...

Nano-Immunotherapy Developed to Improve Lung Cancer Treatment

June 14, 2024 — Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising ...

Why Many Lung Cancer Patients Who Have Never Smoked Have Worse Outcomes

June 13, 2024 — The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been ...

Swimming Microrobots Deliver Cancer-Fighting Drugs to Metastatic Lung Tumors in Mice

June 12, 2024 — Engineers have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown ...

Clinical Trial Shows Promising Results in a Two-Drug Combination That Curbs Methamphetamine Use

June 10, 2024 — A clinical trial on a two-drug therapy for methamphetamine use disorder reduced use of the highly addictive drug for up to 12 weeks after initiation of treatment. Participants in the ADAPT-2 clinical ...

Peptidomimetics Open New Opportunities in Drug Discovery

June 7, 2024 — A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research ...

New Therapeutic Targets to Fight Type 2 Diabetes

June 7, 2024 — One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by ...

Study Identifies Potential Pathway to Reducing Breast Cancer Brain Metastases

June 7, 2024 — A study has identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the ...