Featured Research

from universities, journals, and other organizations

Functional Significance Of Iron Deficiency In Children

Date:
June 6, 1997
Source:
Johns Hopkins Children's Center
Summary:
Children who suffered from severe, chronic iron deficiency as infants have learning and behavior deficits into adolescence.

WASHINGTON---Children who suffered from severe, chronic iron deficiency as infants are disadvantaged with respect to learning and behavior as they enter adolescence, even though their current iron and growth status is excellent, according to a University of Michigan study. Roughly 25 percent of all babies in the world have iron deficiency anemia and many more have iron deficiency without anemia.

Researchers led by Dr. Betsy Lozoff, director of the U-M Center for Human Growth and Development (CHGD) and professor of pediatrics, have been conducting a longitudinal study of 191 infants born in 1981-83 in a lower-middle class community in Costa Rica. The infants, who were screened and treated for iron deficiency, had been previously re-evaluated at five years of age.

Recently, 167 of them were re-evaluated at ages 10-13. "Of the 167 children," said Lozoff, "48 had been severely, chronically iron deficient as infants and 119 had been iron sufficient either before or after iron therapy in infancy. The severe, chronic iron deficient group consisted of children who had had moderate iron-deficiency anemia as infants and those with higher hemoglobin levels with iron deficiency that did not completely correct with iron therapy in infancy."

The most recent evaluation included measures of cognitive and motor functions, scholastic achievement, and behavioral problems. The results were reported last month at the American Pediatric Society Meeting in Washington, D.C.

"At the five-year follow-up, we found that children who had had severe, chronic iron deficiency as infants tested lower than the children who had had better iron status on a variety of measures---visual-motor integration, quantitative or numerical concepts, visual matching, and performance IQ.

"Unfortunately, the trends continued at ages 10-13 and had a negative effect on their scholastic achievement scores," Lozoff said. "Although all of them were in the 'normal range,' we found that the children who had severe, chronic iron deficiency now scored lower on standardized achievement tests---about 7 points lower on tests [100 point scales] of reading, writing and arithmetic, with particularly marked differences in written expression. Sub-tests of IQ measures also determined that they had acquired less general knowledge of the world and were less able to do abstract reasoning. Their motor scores also continued to be lower," Lozoff said.

The children who had severe, chronic iron deficiency also scored higher for behavioral problems, which may have interfered with their learning, Lozoff suggested. "These children had more internalizing problems---they were reported to be more anxious and socially withdrawn and to have more somatic or physical complaints than the children who had had better iron status in infancy. In fact, by U.S. standards, their internalization scores were in the clinical range---that is, they would be considered for mental health evaluation and treatment in the United States."

The researchers will follow the children over the next five years, examining the impact of severe chronic iron deficiency in infancy on classroom grades, retention, need for special education or tutoring, and school dropout rates.

Lozoff's colleagues on the recent follow up study are Eileen Mollen, psychologist and assistant professor, U-M Department of Pediatrics and Communicable Diseases; John Hagen, research scientist at CHGD and U-M professor of psychology; Abraham W. Wolf, assistant professor of psychology, Department of Psychiatry, Case Western Reserve University School of Medicine; and Elias Jimenez, director of research, Hospital Nacional de Ninos, Costa Rica.


Story Source:

The above story is based on materials provided by Johns Hopkins Children's Center. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Children's Center. "Functional Significance Of Iron Deficiency In Children." ScienceDaily. ScienceDaily, 6 June 1997. <www.sciencedaily.com/releases/1997/06/970606121500.htm>.
Johns Hopkins Children's Center. (1997, June 6). Functional Significance Of Iron Deficiency In Children. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/1997/06/970606121500.htm
Johns Hopkins Children's Center. "Functional Significance Of Iron Deficiency In Children." ScienceDaily. www.sciencedaily.com/releases/1997/06/970606121500.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) — Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Reasons Why Teen Birth Rates Are At An All-Time Low

Reasons Why Teen Birth Rates Are At An All-Time Low

Newsy (Aug. 20, 2014) — A CDC report says birth rates among teenagers have been declining for decades, reaching a new low in 2013. We look at several popular explanations. Video provided by Newsy
Powered by NewsLook.com
Common Antibiotic Could Lead To Heart-Related Death

Common Antibiotic Could Lead To Heart-Related Death

Newsy (Aug. 20, 2014) — Danish researchers discovered patients taking clarithromycin have an increased risk of dying from a heart-related issue. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins