Featured Research

from universities, journals, and other organizations

Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients

Date:
September 17, 1998
Source:
Penn State
Summary:
Patients with chronic hepatitis C often take the over-the-counter non-steroidal drug Ibuprofen, otherwise known as Motrin or Advil, to combat joint pain that often accompanies the disease. Even a low dose could lead to unsuspecting liver damage.

HERSHEY, PA-- Patients with chronic hepatitis C often take the over-the-counter non-steroidal drug Ibuprofen, otherwise known as Motrin or Advil, to combat joint pain that often accompanies the disease. Even a low dose could lead to unsuspecting liver damage.

"Patients frequently suffer from joint pain. Often, even physicians will prescribe ibuprofen when they should prescribe Tylenol," explains Thomas Riley, III, M.D., assistant professor of medicine at Penn State's College of Medicine. "The correct recommendation to help the patient is a low dose of Tylenol, about 2 grams per day. That means the patient can take one extra strength Tylenol -- 500 mg -- every six hours or take two every 12 hours."

Riley and his colleagues describe three cases in an article, "Ibuprofen Induced Hepatoxicity in Those With Chronic Hepatitis C: A Case Series," published in the September issue of the American Journal of Gastroenterology.

In each of these three cases the patients have hepatitis C and took over-the-counter ibuprofen. After doing so they all had a flare-up of their hepatitis.

"Many physicians don't want to prescribe Tylenol because it has a reputation of causing liver damage. As long as it is prescribed in the low doses we have discussed it is definitely the best treatment," explains Riley, who is also the medical director for the liver transplant program at The Milton S. Hershey Medical Center of the Penn State Geisinger Health System. He also says where patients with chronic hepatitis C usually have mild elevations in their liver enzymes in the blood, after taking the over-the-counter Ibuprofen these patients experience a ten-fold rise in their enzymes, suggesting significant liver injury.

He adds that if too much medication is taken the patient risks speeding up the process of going from chronic hepatitis to cirrhosis of the liver.

Riley says that about four million Americans are infected with hepatitis C. Some of the more common ways it is contracted are by IV drug use, a blood transfusion or getting a tattoo.

"Many patients can live with hepatitis for perhaps 50 years. However, if too much of the wrong medication is taken or if the patient consumes a lot of alcohol, the process from hepatitis to cirrhosis can speed up," says Riley.

This articles focuses on three cases. Riley says further study is needed of a large group of patients with hepatitis C to determine perhaps an even better approach to this growing problem.


Story Source:

The above story is based on materials provided by Penn State. Note: Materials may be edited for content and length.


Cite This Page:

Penn State. "Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients." ScienceDaily. ScienceDaily, 17 September 1998. <www.sciencedaily.com/releases/1998/09/980917075936.htm>.
Penn State. (1998, September 17). Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/1998/09/980917075936.htm
Penn State. "Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients." ScienceDaily. www.sciencedaily.com/releases/1998/09/980917075936.htm (accessed October 2, 2014).

Share This



More Health & Medicine News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins