Featured Research

from universities, journals, and other organizations

Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients

Date:
September 17, 1998
Source:
Penn State
Summary:
Patients with chronic hepatitis C often take the over-the-counter non-steroidal drug Ibuprofen, otherwise known as Motrin or Advil, to combat joint pain that often accompanies the disease. Even a low dose could lead to unsuspecting liver damage.

HERSHEY, PA-- Patients with chronic hepatitis C often take the over-the-counter non-steroidal drug Ibuprofen, otherwise known as Motrin or Advil, to combat joint pain that often accompanies the disease. Even a low dose could lead to unsuspecting liver damage.

Related Articles


"Patients frequently suffer from joint pain. Often, even physicians will prescribe ibuprofen when they should prescribe Tylenol," explains Thomas Riley, III, M.D., assistant professor of medicine at Penn State's College of Medicine. "The correct recommendation to help the patient is a low dose of Tylenol, about 2 grams per day. That means the patient can take one extra strength Tylenol -- 500 mg -- every six hours or take two every 12 hours."

Riley and his colleagues describe three cases in an article, "Ibuprofen Induced Hepatoxicity in Those With Chronic Hepatitis C: A Case Series," published in the September issue of the American Journal of Gastroenterology.

In each of these three cases the patients have hepatitis C and took over-the-counter ibuprofen. After doing so they all had a flare-up of their hepatitis.

"Many physicians don't want to prescribe Tylenol because it has a reputation of causing liver damage. As long as it is prescribed in the low doses we have discussed it is definitely the best treatment," explains Riley, who is also the medical director for the liver transplant program at The Milton S. Hershey Medical Center of the Penn State Geisinger Health System. He also says where patients with chronic hepatitis C usually have mild elevations in their liver enzymes in the blood, after taking the over-the-counter Ibuprofen these patients experience a ten-fold rise in their enzymes, suggesting significant liver injury.

He adds that if too much medication is taken the patient risks speeding up the process of going from chronic hepatitis to cirrhosis of the liver.

Riley says that about four million Americans are infected with hepatitis C. Some of the more common ways it is contracted are by IV drug use, a blood transfusion or getting a tattoo.

"Many patients can live with hepatitis for perhaps 50 years. However, if too much of the wrong medication is taken or if the patient consumes a lot of alcohol, the process from hepatitis to cirrhosis can speed up," says Riley.

This articles focuses on three cases. Riley says further study is needed of a large group of patients with hepatitis C to determine perhaps an even better approach to this growing problem.


Story Source:

The above story is based on materials provided by Penn State. Note: Materials may be edited for content and length.


Cite This Page:

Penn State. "Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients." ScienceDaily. ScienceDaily, 17 September 1998. <www.sciencedaily.com/releases/1998/09/980917075936.htm>.
Penn State. (1998, September 17). Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/1998/09/980917075936.htm
Penn State. "Possible Dangers Of Taking Over-The-Counter Medications For Hepatitis C Patients." ScienceDaily. www.sciencedaily.com/releases/1998/09/980917075936.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins