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Double-Edged Effect Of Inflammatory Response Discovered After Brain Injury

Date:
July 23, 1999
Source:
University Of Pennsylvania Medical Center
Summary:
Until recently, researchers in the area of head trauma have only concentrated on the biochemical sequence of events in the first few days after an injury. During the past year, however, investigators at the University of Pennsylvania Medical Center have found that the brain undergoes enormous changes for months following the initial damage.

Until recently, researchers in the area of head trauma have only concentrated on the biochemical sequence of events in the first few days after an injury. During the past year, however, investigators at the University of Pennsylvania Medical Center have found that the brain undergoes enormous changes for months following the initial damage. In the latest development in this ongoing work, the team found that tumor necrosis factor (TNF) -- a cytokine molecule that is normally released during inflammation -- may be damaging and then protective to brain-injured tissue, depending on the time course after the injury. The researchers report their findings in this week's issue of the Proceedings of the National Academy of Sciences.


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The above story is based on materials provided by University Of Pennsylvania Medical Center. Note: Materials may be edited for content and length.


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University Of Pennsylvania Medical Center. "Double-Edged Effect Of Inflammatory Response Discovered After Brain Injury." ScienceDaily. ScienceDaily, 23 July 1999. <www.sciencedaily.com/releases/1999/07/990723083745.htm>.
University Of Pennsylvania Medical Center. (1999, July 23). Double-Edged Effect Of Inflammatory Response Discovered After Brain Injury. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/1999/07/990723083745.htm
University Of Pennsylvania Medical Center. "Double-Edged Effect Of Inflammatory Response Discovered After Brain Injury." ScienceDaily. www.sciencedaily.com/releases/1999/07/990723083745.htm (accessed April 16, 2014).

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