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Gene Mutation Extends Lifespan In "I'm Not Dead Yet" Fruitflies

Date:
December 15, 2000
Source:
NIH/National Institute On Aging
Summary:
Mutating a single gene can double the lifespan of fruitflies from 37 days to between 69 and 71 days, while maintaining a high level of functioning and fertility. The gene complex was named Indy as a joking reference to the tag line from Monty Python and the Holy Grail, "I'm not dead yet."

Mutating a single gene can double the lifespan of fruitflies from 37 days to between 69 and 71 days, while maintaining a high level of functioning and fertility. This finding of a research team led by Stephen L. Helfand was supported in part by the National Institute on Aging (NIA), part of the National Institutes of Health.* Their study is reported in the December 14 issue of Science. The gene complex was named Indy as a joking reference to the tag line from Monty Python and the Holy Grail, "I'm not dead yet." This is the third mutation in the fruitfly genome that is reported to extend lifespan. According to Helfand, the Indy gene is associated with the way that the body stores and uses energy.


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The above story is based on materials provided by NIH/National Institute On Aging. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute On Aging. "Gene Mutation Extends Lifespan In "I'm Not Dead Yet" Fruitflies." ScienceDaily. ScienceDaily, 15 December 2000. <www.sciencedaily.com/releases/2000/12/001215082220.htm>.
NIH/National Institute On Aging. (2000, December 15). Gene Mutation Extends Lifespan In "I'm Not Dead Yet" Fruitflies. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2000/12/001215082220.htm
NIH/National Institute On Aging. "Gene Mutation Extends Lifespan In "I'm Not Dead Yet" Fruitflies." ScienceDaily. www.sciencedaily.com/releases/2000/12/001215082220.htm (accessed April 18, 2014).

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