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Epigenetics Research News

March 18, 2024

Top Headlines

 

A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division. ...
While exposure to a single substance like DDT has been shown to create inherited disease susceptibility, a recent study in animals found exposure to multiple different toxicants across generations ...
Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an ...
A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome ...

Latest Headlines

updated 10:50pm EDT

Earlier Headlines

 

A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The ...

More than 2,500 genes exhibit significant sex differences in expression in mouse alveolar type II cells (AT2s), important for keeping the lungs functioning, potentially explaining sex biases in the ...

The gene-silencing complex HUSH might be involved in complex disorders affecting the brain and neurons. However, its mechanism of action remains unclear. Researchers now uncover the in vivo targets ...

Toxicologists have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their ...

Researchers describe how different types of repetitive DNA elements are controlled by the same silencing mechanism in fruit fly ovaries. Central to their findings is an uncharacterized protein that ...

Changing the epigenetic marks on chromosomes leads to altered gene expression in offspring and in grandoffspring, demonstrating 'transgenerational epigenetic inheritance.' Without altering ...

Changes known as epigenetic modifications play an important role in cancer development, among other things. Being able to analyze them quickly and reliably could, for example, contribute ...

A fundamental discovery about a driver of healthy development in embryos could rewrite our understanding of what can be inherited from our parents and how their life experiences may shape ...

In most mammals, females have two X chromosomes and males have one X and one Y chromosome in each of their cells. To avoid a double dose of X-linked genes in females, one of the Xs is silenced early ...

Gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence, according to the results of an animal study. The ...

Researchers have discovered a gene responsible for prenatal death when critical epigenetic instructions are missing from egg cells. The study shows that in mice, failed epigenetic suppression of an ...

Researchers have found that heterozygous loss of the methyl-CpG binding protein Zbtb38 downregulated the expression of the transcription factors Nanog and Sox2, as well as genes involved in epiblast ...

Researchers have revealed how an 'accordion effect' is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing. The finding expands ...

How is the activity of genes regulated by the packaging of DNA? To answer this question, researchers developed a technique to measure both gene expression and DNA packaging at the same ...

Animals often use highly specific signals to warn their herd about approaching predators. Surprisingly, similar behaviors are also observed among plants. Shedding more light on this phenomenon, ...

In humans and other eukaryotes, two principal epigenetic marks are known. A team has discovered a third, novel epigenetic mark -- one formerly known only in bacteria -- in bdelloid rotifers, small ...

A new study has shown that the effects of pollutants can be transmitted over many generations in water fleas and may persist long enough to influence the evolutionary process. The research adds new ...

Researchers discover a 'switch' specific to transcription factors that induce the genes essential for blood vessel development in postnatal periods. Mouse models further showed that the ...

Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is ...

A team has shown that the CLASSY gene family regulates which parts of the genome are turned off in a tissue-specific manner. The work identifies the CLSY genes as major factors underlying epigenetic ...

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