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Mapping the Embryonic Epigenome: How Genes Are Turned on and Off During Early Human Development
A large, multi-institutional
research team has published
a sweeping analysis of how
genes are turned on and off
to direct early human develo ... > full story
Mechanism of Mutant Histone Protein in Childhood Brain Cancer Revealed
Researchers have shown how a
mutated histone protein
inhibits an enzyme, which
normally keeps cell growth
in check, and causes a rare
... > full story
Novel Way Plants Pass Traits to Next Generation: Inheritance Behavior in Corn Breaks Accepted Rules of Genetics
New research explains how
certain traits can pass down
from one generation to the
next – at least in
plants – without
... > full story
Old Mice, Young Blood: Rejuvenating Blood of Mice by Reprogramming Stem Cells That Produce Blood
The blood of young and old
people differs. Scientists
have now rejuvenated the
blood of mice by reversing,
or reprogramming, the stem
... > full story
- Mapping the Embryonic Epigenome: How Genes Are Turned on and Off During Early Human Development
- Mechanism of Mutant Histone Protein in Childhood Brain Cancer Revealed
- Novel Way Plants Pass Traits to Next Generation: Inheritance Behavior in Corn Breaks Accepted Rules of Genetics
- Old Mice, Young Blood: Rejuvenating Blood of Mice by Reprogramming Stem Cells That Produce Blood
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Epigenomics of Stem Cells That Mimic Early Human Development Charted
May 9, 2013 — Scientists have long known that control mechanisms known collectively as “epigenetics” play a critical role in human development, but they did not know precisely how alterations in this ... > full story -
Potential New Way to Detect Colorectal and Other Cancers
April 25, 2013 — A unique new study reveals a novel mechanism explaining the previously unknown root cause of some forms of colorectal ... > full story -
Novel Therapeutic Approaches May Cure Chronic HBV Infection
April 25, 2013 — Exciting new data from early in vitro and in vivo studies targeting covalently closed circular DNA, which may form the basis of a cure for chronic hepatitis B virus ... > full story -
Epigenetic Changes Shed Light on Biological Mechanism of Autism
April 23, 2013 — Scientists have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study is the largest of ... > full story -
Excess Estrogen in Pregnancy Can Silence BRCA1 in Daughters, Increasing Breast Cancer Risk
April 9, 2013 — Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers. They found the DNA repair gene BRCA1 to be silenced in one ... > full story -
KDM1 May Represent a New Therapeutic Target for Glioma
April 7, 2013 — Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to new ... > full story -
More Accurate Markers Identified for Detecting Response to Epigenetic Drugs for Myelodysplastic Syndromes
April 7, 2013 — Researchers have identified and validated two DNA methylation markers that could help physicians to more accurately determine a patient's response to epigenetic drugs for treatment of myelodysplastic ... > full story -
New Drug Target Companion Prognostic Test for Hormone Therapy Resistance
April 1, 2013 — A team of international cancer researchers has identified the signalling pathway that is over-activated in estrogen receptor-positive breast cancer cells that are resistant to hormone therapies such ... > full story -
New Insights Into How Genes Turn on and Off
March 27, 2013 — Researchers have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent of the placental genome has ... > full story -
New Clues in Hunt for Heredity in Type 2 Diabetes
March 19, 2013 — Type 2 diabetes has strong hereditary tendencies and the genes we are born with cannot be changed. However, new research shows that we can modify the function of the genes through the epigenetic ... > full story
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