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Stanford Researchers Find Cause, Possible Cure For Gluten Intolerance

Date:
September 27, 2002
Source:
Stanford University Medical Center
Summary:
A team of investigators led by Stanford University researchers have discovered the cause and a potential treatment for celiac sprue, an autoimmune disease that leads to an inability to digest gluten, a major protein in wheat, rye and barley products. The disease is estimated to afflict as many as 1 in 200 Americans.

STANFORD, Calif. - A team of investigators led by Stanford University researchers have discovered the cause and a potential treatment for celiac sprue, an autoimmune disease that leads to an inability to digest gluten, a major protein in wheat, rye and barley products. The disease is estimated to afflict as many as 1 in 200 Americans. In the Sept. 27 issue of Science, researchers identify a fragment of gluten called gliadin as the celiac culprit. They showed that this fragment is resistant to digestion and is responsible for the intestine-damaging inflammatory response experienced by celiac patients. They also report the use of a dietary enzyme made by a bacterium that can break down the fragment into harmless bits, suggesting future treatment through dietary supplements.


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The above story is based on materials provided by Stanford University Medical Center. Note: Materials may be edited for content and length.


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Stanford University Medical Center. "Stanford Researchers Find Cause, Possible Cure For Gluten Intolerance." ScienceDaily. ScienceDaily, 27 September 2002. <www.sciencedaily.com/releases/2002/09/020927070151.htm>.
Stanford University Medical Center. (2002, September 27). Stanford Researchers Find Cause, Possible Cure For Gluten Intolerance. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2002/09/020927070151.htm
Stanford University Medical Center. "Stanford Researchers Find Cause, Possible Cure For Gluten Intolerance." ScienceDaily. www.sciencedaily.com/releases/2002/09/020927070151.htm (accessed April 16, 2014).

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