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West Nile Virus Capsid Protein Causes Encephalitic Inflammation By Triggering Cell Suicide

Date:
December 11, 2002
Source:
University Of Pennsylvania Medical Center
Summary:
The protein that forms the protective capsid surrounding the West Nile virus genetic material may contribute to the deadly inflammation associated with the virus. West Nile virus, which has rapidly spread across the United States, causes neurological symptoms and encephalitis, which can result in paralysis or death. According to researchers at the University of Pennsylvania School of Medicine, the West Nile virus capsid (WNV-Cp) is a destructive protein that can trigger apoptosis – the automatic self-destructive program within cells – inside infected cells, possibly adding to the damage caused by the virus.

Philadelphia, PA – The protein that forms the protective capsid surrounding the West Nile virus genetic material may contribute to the deadly inflammation associated with the virus. West Nile virus, which has rapidly spread across the United States, causes neurological symptoms and encephalitis, which can result in paralysis or death. According to researchers at the University of Pennsylvania School of Medicine, the West Nile virus capsid (WNV-Cp) is a destructive protein that can trigger apoptosis – the automatic self-destructive program within cells – inside infected cells, possibly adding to the damage caused by the virus. Their findings are presented in the December issue of Emerging Infectious Diseases, a journal available on the Centers for Disease Control and Prevention (CDC) Web site.


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The above story is based on materials provided by University Of Pennsylvania Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Pennsylvania Medical Center. "West Nile Virus Capsid Protein Causes Encephalitic Inflammation By Triggering Cell Suicide." ScienceDaily. ScienceDaily, 11 December 2002. <www.sciencedaily.com/releases/2002/12/021211084205.htm>.
University Of Pennsylvania Medical Center. (2002, December 11). West Nile Virus Capsid Protein Causes Encephalitic Inflammation By Triggering Cell Suicide. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2002/12/021211084205.htm
University Of Pennsylvania Medical Center. "West Nile Virus Capsid Protein Causes Encephalitic Inflammation By Triggering Cell Suicide." ScienceDaily. www.sciencedaily.com/releases/2002/12/021211084205.htm (accessed April 18, 2014).

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