Featured Research

from universities, journals, and other organizations

Bacterial Viruses Make Cheap Easy Vaccines

Date:
March 10, 2003
Source:
American Society For Microbiology
Summary:
Genetically altered bacterial viruses appear to be more effective than naked DNA in eliciting an immune response and could be a new strategy for a next generation of vaccines that are easy to produce and store, say researchers from Moredun Research Institute in the United Kingdom.

BALTIMORE – March 10, 2003 – Genetically altered bacterial viruses appear to be more effective than naked DNA in eliciting an immune response and could be a new strategy for a next generation of vaccines that are easy to produce and store, say researchers from Moredun Research Institute in the United Kingdom.

"In theory, millions of doses can be grown within a matter of days using simple equipment, media and procedures," says John March, one of lead researchers presenting findings at the American Society for Microbiology's Biodefense Research Meeting.

Bacteriophages are viruses that infect bacteria but not humans. In this particular study, March and his colleagues used a bacteriophage as a vehicle for genes from hepatitis B virus in mice and compared its ability to elicit a protective immune response with a vaccine made of naked DNA. They found that not only could the bacteriophage induce an immune response, the number of bacteriophage they needed was less than 1 percent of the number of pieces of naked DNA required to mount an effective immune response.

Using bacteriophages to deliver vaccine components offers several advantages over vaccination with naked DNA, says March. The DNA is protected inside the protein shell of the virus making it longer lasting and easier to store. In addition, bacteriophages have a large cloning capacity, making large-scale production cheap, easy and extremely rapid – important attributes considering the current bioterrorism threat when sudden demands may be placed on vaccine stocks.

###

The American Society for Microbiology (ASM) is the largest single life science society, composed of over 42,000 scientists, teachers, physicians, and health professionals. Its mission is to promote research and training in the microbiological sciences and to assist communication between scientists, policymakers, and the public to improve health, economic well being, and the environment. Further information on the ASM Biodefense Research Meeting can be found online at http://www.asmbiodefense.org .


Story Source:

The above story is based on materials provided by American Society For Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society For Microbiology. "Bacterial Viruses Make Cheap Easy Vaccines." ScienceDaily. ScienceDaily, 10 March 2003. <www.sciencedaily.com/releases/2003/03/030310064342.htm>.
American Society For Microbiology. (2003, March 10). Bacterial Viruses Make Cheap Easy Vaccines. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2003/03/030310064342.htm
American Society For Microbiology. "Bacterial Viruses Make Cheap Easy Vaccines." ScienceDaily. www.sciencedaily.com/releases/2003/03/030310064342.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com
Michigan Man Sees Thanks to 'bionic Eye'

Michigan Man Sees Thanks to 'bionic Eye'

AP (Apr. 23, 2014) A legally blind Michigan man is 'seeing something new every day' thanks to a high-tech retinal implant procedure. He's one of the first in the country to receive a 'bionic eye' since the federal government approved the surgery. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins