Vascular disease pertains to the disorders that affect our arteries and veins. For the three most common types of vascular disease -- carotid, aortic and peripheral – aging is a major risk factor. Recent studies suggest that pathological changes not only predispose the vasculature to disease but also impair compensatory adaptations to various stimuli including shear force and injury. Other studies have demonstrated a progressive increase in oxidative stress, activation of inflammatory mediators, and increasing endothelial dysfunction in both humans and animals.
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