Featured Research

from universities, journals, and other organizations

Researcher Uses Bioprinter To Print Three-Dimensional Cellular Structures

Date:
February 18, 2004
Source:
University Of Missouri-Columbia
Summary:
Thanks to a University of Missouri-Columbia researcher, his colleagues, and a very special printing device, artificially manufacturing an organ compatible with the organism that will receive the organ is one step closer to reality.

Thanks to a University of Missouri-Columbia researcher, his colleagues, and a very special printing device, artificially manufacturing an organ compatible with the organism that will receive the organ is one step closer to reality.

Gabor Forgacs, a biological physicist at MU, and his research team found that given the right cues, cells will self assemble into an organ module. Forgacs’ work is documented in the article “Engineering Biological Structures of Prescribed Shape Using Self-Assembling Multicellular Systems,” which appears in this week’s issue of Proceedings of the National Academy of Sciences (PNAS).

Forgacs’ lab used specially designed printing devices loaded with spherical cell aggregates (i.e. multicellular assemblies) as drops of “bio-ink” to create tubular structures. The printer first drops the aggregates in a circular shape onto a layer of gel. Another layer of the gel is added on top of the first, and the printer then repeats the process, stacking the aggregate rings. Later, the aggregates fuse to form the tube.

“A large part of the body is made of tubes,” Forgacs said. “We can now make 3-D hollow biological tubes and organ modules, which potentially could be used as grafts, or for doing research on a particular drug using an organ substitute and thus avoiding any hazard. The next step is the construction of functional organ modules, prepared outside of the living organism and then implanted into the organism.”

Forgacs says the chances of a body rejecting the new organ constructed this way would be removed because it would be assembled from the body’s own cells. The work also proves the process does not require a complete “manual” to build potential replacement organs.

“It is far too complex to build a biologically fully functional organ,” Forgacs said. “This study suggests you have to provide the proper environment and place the cell aggregates in the correct geometrical shape. After that, the biological system takes over and completes the structure.”

The researchers’ next steps are to obtain a patent for the bio-ink as well as further funding for the research. An industrial partner to help provide the printer needed to conduct future research is also needed.

More information on Forgacs’ lab can be found at http://www.missouri.edu/~forglab


Story Source:

The above story is based on materials provided by University Of Missouri-Columbia. Note: Materials may be edited for content and length.


Cite This Page:

University Of Missouri-Columbia. "Researcher Uses Bioprinter To Print Three-Dimensional Cellular Structures." ScienceDaily. ScienceDaily, 18 February 2004. <www.sciencedaily.com/releases/2004/02/040218080011.htm>.
University Of Missouri-Columbia. (2004, February 18). Researcher Uses Bioprinter To Print Three-Dimensional Cellular Structures. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2004/02/040218080011.htm
University Of Missouri-Columbia. "Researcher Uses Bioprinter To Print Three-Dimensional Cellular Structures." ScienceDaily. www.sciencedaily.com/releases/2004/02/040218080011.htm (accessed August 2, 2014).

Share This




More Matter & Energy News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Tesla, Panasonic Ink Deal To Make Huge Battery 'Gigafactory'

Tesla, Panasonic Ink Deal To Make Huge Battery 'Gigafactory'

Newsy (July 31, 2014) The deal will help build a massive battery factory that Tesla says will produce 500,000 lithium batteries by 2020. Video provided by Newsy
Powered by NewsLook.com
Britain Testing Driverless Cars on Roadways

Britain Testing Driverless Cars on Roadways

AP (July 30, 2014) British officials said on Wednesday that driverless cars will be tested on roads in as many as three cities in a trial program set to begin in January. Officials said the tests will last up to three years. (July 30) Video provided by AP
Powered by NewsLook.com
7 Ways to Use Toothpaste: Howdini Hacks

7 Ways to Use Toothpaste: Howdini Hacks

Howdini (July 30, 2014) Fresh breath and clean teeth are great, but have you ever thought, "my toothpaste could be doing more". Well, it can! Lots of things! Howdini has 7 new uses for this household staple. Video provided by Howdini
Powered by NewsLook.com
Smoked: 2015 Ducati Diavel Vs 2014 Chevy Corvette Stingray Drag Race

Smoked: 2015 Ducati Diavel Vs 2014 Chevy Corvette Stingray Drag Race

Cycle World (July 30, 2014) The Bonnier Motorcycle Group presents Smoked; a three part video series. In this episode the 2015 Ducati Diavel takes on the 2014 Chevy Corvette Stingray Video provided by Cycle World
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins