Featured Research

from universities, journals, and other organizations

Researchers Discover Cold Virus Can 'Hit And Hide'

Date:
April 26, 2004
Source:
Imperial College Of Science, Technology And Medicine
Summary:
An international team of researchers has discovered that respiratory syncytial virus (RSV), a common cold virus causing bronchiolitis in children, can act as a 'hit and hide' virus.

An international team of researchers has discovered that respiratory syncytial virus (RSV), a common cold virus causing bronchiolitis in children, can act as a 'hit and hide' virus. It was thought that the virus could only survive in the body for a few days, but these new results show that the virus can survive for many months or years, perhaps causing long-term effects on health, such as damage to the lungs.

The research, published in this month's American Journal of Respiratory and Critical Care Medicine, was a joint project between Imperial College London, St Mary's Hospital, London and the Ruhr-Universitat Bochum, Germany.

Professor Peter Openshaw, from Imperial College London and St Mary's Hospital, and one of the papers authors, comments: "These studies show that RSV is a 'hit and hide' virus, rather like HIV, herpes or some hepatitis viruses. The symptoms seem to go away but the virus is just hiding, waiting for a chance to re-emerge and begin infecting other people."

The researchers infected mice with the human RSV, and found that after 14 days, the virus could no longer be found in samples taken from the airways, but tell-tale traces of the virus's genetic material (viral RNA) were still found lying dormant in lung tissue over 100 days later.

The team believes that this may also be the case in humans, and that long after the initial symptoms, such as coughs and sneezes, have disappeared, the virus could lie dormant in the body. It is possible that the recurrent wheezing which occurs in children who have suffered from bronchiolitis may be due to virus hidden in the lung.

Professor Openshaw says: "Some people may be 'carriers', able to act as a source of new outbreaks in children. If RSV is a 'hit and hide' virus, this could explain where this virus goes in the summer and where it comes from each winter. If the virus is able to lie dormant in previously infected individuals, it could re-emerge when the conditions are right and cause the outbreaks that fill our children's wards each winter."

RSV is very common infecting most children during their first year of life and for some infants RSV leads to bronchiolitis, one of the major causes of infant hospitalisation in the Western world. Around 40 percent of infants who experience bronchiolitis as a result of RSV infection are subsequently affected by recurring wheeze and up to a third can also suffer with childhood asthma.

This research was supported by grants from the Wellcome Trust and the Bundes Ministerium fur Bildung and Forschung.


Story Source:

The above story is based on materials provided by Imperial College Of Science, Technology And Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Imperial College Of Science, Technology And Medicine. "Researchers Discover Cold Virus Can 'Hit And Hide'." ScienceDaily. ScienceDaily, 26 April 2004. <www.sciencedaily.com/releases/2004/04/040426055429.htm>.
Imperial College Of Science, Technology And Medicine. (2004, April 26). Researchers Discover Cold Virus Can 'Hit And Hide'. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2004/04/040426055429.htm
Imperial College Of Science, Technology And Medicine. "Researchers Discover Cold Virus Can 'Hit And Hide'." ScienceDaily. www.sciencedaily.com/releases/2004/04/040426055429.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
EU Ministers and Experts Meet to Discuss Ebola Reponse

EU Ministers and Experts Meet to Discuss Ebola Reponse

AFP (Sep. 15, 2014) The European Commission met on Monday to coordinate aid that the EU can offer to African countries affected by the Ebola outbreak. Duration: 00:58 Video provided by AFP
Powered by NewsLook.com
Despite The Risks, Antibiotics Still Overprescribed For Kids

Despite The Risks, Antibiotics Still Overprescribed For Kids

Newsy (Sep. 15, 2014) A new study finds children are prescribed antibiotics twice as often as is necessary. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins