Featured Research

from universities, journals, and other organizations

Hepatitis C: Surprise Finding Could Lead To Vaccine

Date:
August 25, 2004
Source:
University Of New South Wales
Summary:
New research from the University of New South Wales shows some people may repeatedly be able to clear hepatitis C virus from their bodies, without any biological traces of the potentially serious infection.

New research from the University of New South Wales shows some people may repeatedly be able to clear hepatitis C virus from their bodies, without any biological traces of the potentially serious infection.

The surprise finding could lead to the development of a vaccine against the virus, which currently affects around 210,000 Australians and can cause liver cancer and liver failure. The research has just been published in the prestigious Journal of Infectious Diseases.

The study found some individuals with high-risk behaviour, involving blood-to-blood contact, appear to develop "protective immunity" against the virus, thereby becoming resistant to persistent infection.

The researchers identified 160 prisoners who were free of the infection and tracked them on a monthly basis whilst in gaol. This entailed blood collection and recording episodes likely to put the prisoners at risk for transmission of hepatitis C, such as injecting drug use or tattooing.

Over the course of the study, four prisoners became infected with hepatitis C, yet they all went on to clear the virus without suffering any symptoms or developing antibodies against the virus. Instead it appeared that another arm of the immune system based on specialised white blood cells, or T cells, might be active in fighting the virus.

"It is possible that they had been infected in the past, perhaps on several occasions and that may be why they were able to clear the virus efficiently and without developing antibodies," said UNSW Professor Andrew Lloyd, who is in the School of Medical Sciences.

This cellular immunity appears similar to that found in some Kenyan prostitutes who appear to have protective immunity from HIV. These prostitutes are resistant to becoming HIV positive, despite repeatedly having unprotected sex with clients who are infected.

The researchers have found a similar pattern of cellular immunity to hepatitis C in another high-risk group - injecting drug users. They ultimately hope to reproduce a similar pattern of protective immunity with a synthetic vaccine.


Story Source:

The above story is based on materials provided by University Of New South Wales. Note: Materials may be edited for content and length.


Cite This Page:

University Of New South Wales. "Hepatitis C: Surprise Finding Could Lead To Vaccine." ScienceDaily. ScienceDaily, 25 August 2004. <www.sciencedaily.com/releases/2004/08/040825094845.htm>.
University Of New South Wales. (2004, August 25). Hepatitis C: Surprise Finding Could Lead To Vaccine. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2004/08/040825094845.htm
University Of New South Wales. "Hepatitis C: Surprise Finding Could Lead To Vaccine." ScienceDaily. www.sciencedaily.com/releases/2004/08/040825094845.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins