Featured Research

from universities, journals, and other organizations

Hepatitis C: Surprise Finding Could Lead To Vaccine

Date:
August 25, 2004
Source:
University Of New South Wales
Summary:
New research from the University of New South Wales shows some people may repeatedly be able to clear hepatitis C virus from their bodies, without any biological traces of the potentially serious infection.

New research from the University of New South Wales shows some people may repeatedly be able to clear hepatitis C virus from their bodies, without any biological traces of the potentially serious infection.

The surprise finding could lead to the development of a vaccine against the virus, which currently affects around 210,000 Australians and can cause liver cancer and liver failure. The research has just been published in the prestigious Journal of Infectious Diseases.

The study found some individuals with high-risk behaviour, involving blood-to-blood contact, appear to develop "protective immunity" against the virus, thereby becoming resistant to persistent infection.

The researchers identified 160 prisoners who were free of the infection and tracked them on a monthly basis whilst in gaol. This entailed blood collection and recording episodes likely to put the prisoners at risk for transmission of hepatitis C, such as injecting drug use or tattooing.

Over the course of the study, four prisoners became infected with hepatitis C, yet they all went on to clear the virus without suffering any symptoms or developing antibodies against the virus. Instead it appeared that another arm of the immune system based on specialised white blood cells, or T cells, might be active in fighting the virus.

"It is possible that they had been infected in the past, perhaps on several occasions and that may be why they were able to clear the virus efficiently and without developing antibodies," said UNSW Professor Andrew Lloyd, who is in the School of Medical Sciences.

This cellular immunity appears similar to that found in some Kenyan prostitutes who appear to have protective immunity from HIV. These prostitutes are resistant to becoming HIV positive, despite repeatedly having unprotected sex with clients who are infected.

The researchers have found a similar pattern of cellular immunity to hepatitis C in another high-risk group - injecting drug users. They ultimately hope to reproduce a similar pattern of protective immunity with a synthetic vaccine.


Story Source:

The above story is based on materials provided by University Of New South Wales. Note: Materials may be edited for content and length.


Cite This Page:

University Of New South Wales. "Hepatitis C: Surprise Finding Could Lead To Vaccine." ScienceDaily. ScienceDaily, 25 August 2004. <www.sciencedaily.com/releases/2004/08/040825094845.htm>.
University Of New South Wales. (2004, August 25). Hepatitis C: Surprise Finding Could Lead To Vaccine. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2004/08/040825094845.htm
University Of New South Wales. "Hepatitis C: Surprise Finding Could Lead To Vaccine." ScienceDaily. www.sciencedaily.com/releases/2004/08/040825094845.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins