Featured Research

from universities, journals, and other organizations

Vaccinating Wildlife Can Reduce Human Risk For Lyme Disease

Date:
December 24, 2004
Source:
Yale University
Summary:
Direct field evidence shows that Lyme disease in humans can be prevented by vaccinating wildlife, researchers in the Department of Epidemiology and Public Health at Yale School of Medicine report in the Proceedings of the National Academy of Sciences.

New Haven, Conn. -- Direct field evidence shows that Lyme disease in humans can be prevented by vaccinating wildlife, researchers in the Department of Epidemiology and Public Health at Yale School of Medicine report in the Proceedings of the National Academy of Sciences.

Related Articles


In a four-year study of isolated woodlands near New Haven, nearly 1,000 white-footed mice were trapped and either vaccinated against Lyme disease or given a placebo. Fewer deer ticks tested positive for Lyme disease in the experimental plots where mice had been vaccinated. Fewer ticks carrying infection reduced the risk for humans getting Lyme disease from a tick bite.

“Vaccinating wildlife increases our prevention options,” said principal investigator Durland Fish, professor of epidemiology at Yale, who led the study with Jean Tsao, now at Michigan State University and microbiologist Alan Barbour at University of California at Irvine. “Despite a record increase in cases, efforts to prevent Lyme disease with a human vaccine were set back in 2002 when it was pulled from the market due to poor sales.”

Although the study showed significant reduction in risk and was the first demonstration of a wildlife vaccination effect for any vector-borne disease, the reduction was not as great as the investigators had hoped.

A surprising result was that mice are not as important in maintaining the Lyme disease bacterium in nature as previous studies showed. “If only mice were responsible for infecting the ticks, we would have seen a much greater reduction,” Fish explained. “We now believe that mice are responsible for only 27 to 55 percent of the infection found in ticks. This changes our view on how Lyme disease is circulated between wildlife and ticks.”

Fish said that in addition to mice, other animals must receive Lyme disease vaccination in order to further reduce risk to humans. Oral vaccines, similar to those currently used against rabies, could be developed for Lyme and other vector-borne human diseases that are maintained by wildlife, including West Nile encephalitis.

Co-authors include J. Timothy Woolton, Jonas Bunkis and Maria Gabriela Luna.

###

Citation: PNAS Vol. 101 No. 50 December 13, 2004.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Vaccinating Wildlife Can Reduce Human Risk For Lyme Disease." ScienceDaily. ScienceDaily, 24 December 2004. <www.sciencedaily.com/releases/2004/12/041219134428.htm>.
Yale University. (2004, December 24). Vaccinating Wildlife Can Reduce Human Risk For Lyme Disease. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2004/12/041219134428.htm
Yale University. "Vaccinating Wildlife Can Reduce Human Risk For Lyme Disease." ScienceDaily. www.sciencedaily.com/releases/2004/12/041219134428.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins