Featured Research

from universities, journals, and other organizations

Breast Cancer Treatment Reduces Risk Of Heart Disease

Date:
February 22, 2005
Source:
John Wiley & Sons, Inc.
Summary:
Women with breast cancer treated with the anti-estrogen drug tamoxifen are at significantly less risk of having a heart attack or symptoms of heart stress such as angina, according to a new study.

Women with breast cancer treated with the anti-estrogen drug tamoxifen are at significantly less risk of having a heart attack or symptoms of heart stress such as angina, according to a new study. The study, published in the March 15, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, finds the benefit becomes pronounced within two years of therapy and is maintained throughout its use.

Tamoxifen has been shown to reduce the risk of breast cancer recurrence by as much as 50 percent. In addition, increasing evidence indirectly supports its protective effects on the heart. Studies have shown women taking tamoxifen show reductions in markers of cardiac disease, such as bad cholesterol and homocysteine. However, there is little direct evidence of tamoxifen's heart protective benefits by way of reduced morbidity or mortality.

To evaluate its hypothesized cardioprotective affects, Brian D. Bradbury, D.Sc., M.A. and a team of investigators from Boston University's Schools of Medicine and Public Health reviewed the records of 3030 breast cancer patients treated with tamoxifen and 4233 patients with other cancers not treated with tamoxifen.

Women treated with tamoxifen were less likely to develop symptomatic heart disease than those who did not receive tamoxifen. On further analysis current use of tamoxifen was associated with significantly reduced risk of heart disease. Moreover, the reduced heart disease effects were observed in women who had completed less than two years of therapy and continued throughout the duration of the five years of recommended therapy.

The authors conclude, "These data are consistent with the proposition that treatment with tamoxifen for women with breast cancer may additionally lower a woman's risk of developing ischemic heart disease."

###

Article: "Tamoxifen-Treated Breast Carcinoma Patients and the Risk of Acute Myocardial Infarction and Newly-Diagnosed Angina," Brian D. Bradbury, Timothy L. Lash, James A. Kaye, Susan S. Jick, CANCER; Published Online: February 14, 2005 (DOI: 10.1002.cncr.20900); Print Issue Date: March 15, 2005.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Breast Cancer Treatment Reduces Risk Of Heart Disease." ScienceDaily. ScienceDaily, 22 February 2005. <www.sciencedaily.com/releases/2005/02/050218131416.htm>.
John Wiley & Sons, Inc.. (2005, February 22). Breast Cancer Treatment Reduces Risk Of Heart Disease. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2005/02/050218131416.htm
John Wiley & Sons, Inc.. "Breast Cancer Treatment Reduces Risk Of Heart Disease." ScienceDaily. www.sciencedaily.com/releases/2005/02/050218131416.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com
How A 'Rule Of Thumb' Could Slow Down Drinking

How A 'Rule Of Thumb' Could Slow Down Drinking

Newsy (Aug. 28, 2014) A study suggests people who follow a "rule of thumb" when pouring wine dispense less than those who don't have a particular amount in mind. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins