Featured Research

from universities, journals, and other organizations

Fiber Supplements May Lower Cardiovascular Risk In Type 2 Diabetics

Date:
April 30, 2005
Source:
American Heart Association
Summary:
Fiber supplements lower "bad" low-density lipoprotein (LDL) cholesterol and increase "good" high-density lipoprotein (HDL) cholesterol in people with type 2 diabetes.

WASHINGTON, D.C., April 30 -- Fiber supplements lower "bad" low-density lipoprotein (LDL) cholesterol and increase "good" high-density lipoprotein (HDL) cholesterol in people with type 2 diabetes, according to a study presented at the American Heart Association's Sixth Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.

High blood cholesterol is a risk factor for cardiovascular disease. Cardiovascular disease is the leading cause of diabetes-related death, according to the American Heart Association. Type 2 diabetes occurs when the body can't produce or properly use insulin to turn food into energy.

Supplements that increase dietary fiber reduce blood cholesterol levels in the general population, which prompted researchers at Unicity International in Orem, Utah, to study its effect in people with type 2 diabetes.

"The remarkable observation is that this works on two sides: It decreased LDL and increased HDL by significant amounts at 90 days," said the study's lead author, Peter J. Verdegem, Ph.D., chief science officer at Unicity International. "This approach is virtually free of side effects. It opens up an alternative treatment option."

The study is one of the first to examine the effect of fiber in cardiovascular risk reduction for people with type 2 diabetes, Verdegem said.

The 78 participants in the open label trial had type 2 diabetes and averaged 59 years old. Researchers measured the participants' total blood cholesterol, triglycerides, LDL and HDL at baseline and again at 90 days.

Cholesterol is a soft, waxy fat that the body uses to form cell membranes and perform other important functions. Lipoproteins transport cholesterol through the body. LDL escorts cholesterol through the circulatory system; HDL carries it to the liver where it it can be eliminated.

Elevated cholesterol levels can raise the risk of hard deposits called plaques forming in the arteries, which increases the risk of heart attack and stroke. LDL levels of 160 milligrams per deciliter (mg/dL) and above are considered high.

Soluble fiber helps lower blood cholesterol levels. However, most adults in the United States do not consume enough dietary fiber. Average daily intake for adults is 15 grams (g); 25g to 30g of fiber is recommended.

"The product (a fiber supplement) was designed to fill that gap between the real intake and the advised intake," Verdegem said.

Study participants received 10g to 15g of BiosLife 2, an over-the-counter fiber supplement manufactured by Unicity International. The drink contains both soluble and insoluble fiber from guar gum, gum arabic, locust bean gum, pectin and oat fiber dispersed in calcium carbonate. It was administered in 5-gram doses two to three times daily 5 to 10 minutes before eating.

"When it is in the intestines, the fiber decreases reabsorption of cholesterol from a meal," Verdegem said.

At the end of the study, total cholesterol had dropped from 215 mg/dL to 184 mg/dL, a 14.4 percent decrease. Triglycerides also improved, dropping from 299 mg/dL to 257 mg/dL, a 14 percent decrease.

LDL decreased from 129 mg/dL to 92 mg/dL -- a 28.7 percent improvement. HDL rose from 43 mg/dL to 55 mg/dL -- a 21.8 percent increase. "With a normal pharmaceutical intervention, you see a decrease in LDL but not an increase in HDL to these levels," Verdegem said. "It is usually only a one-sided effect."

Statin drugs are among the most commonly used cholesterol-lowering medications. Verdegem said the study demonstrates that dietary fiber supplements may be an alternative to statins for people with moderately high cholesterol who are unable or unwilling to take statins.

Co-authors are Steven H. Freed and David J. Joffe, R.Ph.



Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Fiber Supplements May Lower Cardiovascular Risk In Type 2 Diabetics." ScienceDaily. ScienceDaily, 30 April 2005. <www.sciencedaily.com/releases/2005/04/050430103506.htm>.
American Heart Association. (2005, April 30). Fiber Supplements May Lower Cardiovascular Risk In Type 2 Diabetics. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2005/04/050430103506.htm
American Heart Association. "Fiber Supplements May Lower Cardiovascular Risk In Type 2 Diabetics." ScienceDaily. www.sciencedaily.com/releases/2005/04/050430103506.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins