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A Molecule Impedes The Destruction Of The 'Brucella' Bacteria

Date:
June 15, 2005
Source:
Elhuyar Fundazioa
Summary:
Research carried out with the participation of the University of Navarra has shown how a determinate molecule helps an important pathogen, Brucella abortus, escape destruction within the cells charged with eliminating infectious agents (macrophages). This research has been published in the journal Nature Immunology.

Research carried out with the participation of the University of Navarra has shown how a determinate molecule helps an important pathogen, Brucella abortus, escape destruction within the cells charged with eliminating infectious agents (macrophages). This research has been published in the journal Nature Immunology.

Brucella is a model of an intracellular parasite, a category that includes other important bacteria, such as those of tuberculosis or legionelosis. Brucella penetrates the macrophages within membranous vesicles that are not fused with lysosomes (structures containing cellular products necessary to destroy bacteria) as occurs in other micro-organisms. On the contrary, they reach certain compartments within the macrophage. Here the bacteria multiply and establish a chain of events that determine the illness.

Brucellosis, the illness caused by these bacteria, is of great importance worldwide, with millions of human beings and domestic animals affected. This discovery not only means new useful ideas for other researchers, but also the enhanced knowledge of a very important pathogen. From this knowledge useful products, such as new vaccines, can be derived.


Story Source:

The above story is based on materials provided by Elhuyar Fundazioa. Note: Materials may be edited for content and length.


Cite This Page:

Elhuyar Fundazioa. "A Molecule Impedes The Destruction Of The 'Brucella' Bacteria." ScienceDaily. ScienceDaily, 15 June 2005. <www.sciencedaily.com/releases/2005/06/050615060847.htm>.
Elhuyar Fundazioa. (2005, June 15). A Molecule Impedes The Destruction Of The 'Brucella' Bacteria. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2005/06/050615060847.htm
Elhuyar Fundazioa. "A Molecule Impedes The Destruction Of The 'Brucella' Bacteria." ScienceDaily. www.sciencedaily.com/releases/2005/06/050615060847.htm (accessed October 21, 2014).

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