Featured Research

from universities, journals, and other organizations

Does Zinc Fight Prostate Cancer?

Date:
June 20, 2005
Source:
USDA / Agricultural Research Service
Summary:
Scientists have known for decades that zinc may play a role in maintaining the health of the prostate, the walnut-size gland in males, located just behind the bladder. Now, studies led by Agricultural Research Service (ARS) geneticist Liping Huang are providing new details about how zinc in the foods we eat might keep prostate cancer cells from proliferating and spreading.

Geneticist Liping Huang's studies of zinc in prostate cells may reveal more about the role of this nutrient in human prostate health.
Credit: Photo by Peggy Greb

Scientists have known for decades that zinc may play a role in maintaining the health of the prostate, the walnut-size gland in males, located just behind the bladder. Now, studies led by Agricultural Research Service (ARS) geneticist Liping Huang are providing new details about how zinc in the foods we eat might keep prostate cancer cells from proliferating and spreading.

Related Articles


Prostate cancer is the second most common cause of cancer-related death among American men.

Huang is based at the ARS Western Human Nutrition Research Center in Davis, Calif. She's investigating the roles of zinc-transporter proteins, which move zinc in and out of cells in tissue, such as that in the prostate.

In a series of laboratory experiments, Huang and colleagues compared levels of zinc and zinc-transporter proteins in certain cancerous and noncancerous human prostate cells known as epithelial cells. They exposed the cells to a solution of zinc, then found that the cancerous cells accumulated lower levels of zinc compared to the normal cells. That might be explained by another of the team's findings: The cancerous cells had lower levels of a zinc-transporter protein known as ZIP1.

Although another zinc-ferrying-protein, ZIP3, was present in the cancer cells, it wasn't in the correct location.

In all, the results suggest that reduced levels of one transporter protein, ZIP1, and mislocation of another, ZIP3, may play a role in prostate cancer's progression. These preliminary findings are the first to provide direct evidence of the difference in levels and locations of zinc-transporter proteins in healthy and cancerous prostate epithelial cells.

For the experiments, Huang used cells that had the same genetic background. Dissimilar genetic backgrounds could have skewed test results.

ARS, the U.S. Department of Agriculture's chief scientific research agency, and the National Institutes of Health of the U.S. Department of Health and Human Services, are funding the research.


Story Source:

The above story is based on materials provided by USDA / Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA / Agricultural Research Service. "Does Zinc Fight Prostate Cancer?." ScienceDaily. ScienceDaily, 20 June 2005. <www.sciencedaily.com/releases/2005/06/050619193456.htm>.
USDA / Agricultural Research Service. (2005, June 20). Does Zinc Fight Prostate Cancer?. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2005/06/050619193456.htm
USDA / Agricultural Research Service. "Does Zinc Fight Prostate Cancer?." ScienceDaily. www.sciencedaily.com/releases/2005/06/050619193456.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins