Featured Research

from universities, journals, and other organizations

Link Between Alzheimer's Disease And Traumatic Brain Damage Clarified

Date:
August 16, 2005
Source:
VIB, Flanders Interuniversity Institute of Biotechnology
Summary:
This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer's disease. The researchers discovered the function of one of the most important proteins related to Alzheimer's disease. They have indicated that the protein stimulates the growth of nerve paths in the brain, which is essential for recovery after brain damage.

Leuven, Belgium – This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer's disease. The researchers, this time connected to the Catholic University of Leuven, discovered the function of one of the most important proteins related to Alzheimer's disease. They have indicated that the protein stimulates the growth of nerve paths in the brain, which is essential for recovery after brain damage. The results are published in the authoritative journal EMBO Journal.

The normal function of the amyloidal precursor protein or APP clarified It has been known for several years that APP is relevant in Alzheimer's disease. APP is the precursor of the amyloidal- protein that causes the typical 'plaques' in the brains of patients. The normal function of APP was, however, not known. Maarten Leyssen and his colleagues have indicated that APP stimulates the development of nerve paths. Intact nerve paths are essential for the proper functioning of the brain. These connections can be damaged after traumatic brain damage resulting in the improper functioning of the brain. APP is responsible for stimulating the development of new nerve paths.

APP and Alzheimer's disease

These results also aid better understanding of certain aspects of Alzheimer's disease, where APP plays a major role. The fruit fly – an ideal model to study the brain's action – indicates that APP increases considerably after brain damage, namely in areas where new nerve paths need to be formed. Because more APP is made, more plaques can develop in the brain, a typical symptom of Alzheimer's disease. For the first time the results of VIB researchers explain the strong link between brain damage and Alzheimer's disease: not only do patients with major brain damage have more chance of developing Alzheimer's disease later on in life, their brains also often show plaques that strongly resemble those of Alzheimer patients.


Story Source:

The above story is based on materials provided by VIB, Flanders Interuniversity Institute of Biotechnology. Note: Materials may be edited for content and length.


Cite This Page:

VIB, Flanders Interuniversity Institute of Biotechnology. "Link Between Alzheimer's Disease And Traumatic Brain Damage Clarified." ScienceDaily. ScienceDaily, 16 August 2005. <www.sciencedaily.com/releases/2005/08/050814164946.htm>.
VIB, Flanders Interuniversity Institute of Biotechnology. (2005, August 16). Link Between Alzheimer's Disease And Traumatic Brain Damage Clarified. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2005/08/050814164946.htm
VIB, Flanders Interuniversity Institute of Biotechnology. "Link Between Alzheimer's Disease And Traumatic Brain Damage Clarified." ScienceDaily. www.sciencedaily.com/releases/2005/08/050814164946.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins