Featured Research

from universities, journals, and other organizations

Common Pesticide May Reduce Fertility In Women

Date:
September 12, 2005
Source:
Yale University
Summary:
Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.

Methoxychlor (MXC), a common insect pesticide used on food crops, mayinterfere with proper development and function of the reproductivetract, leading to reduced fertility in women, researchers at YaleSchool of Medicine write in the August issue of Endocrinology.

Related Articles


The researchers found that MXC, which was manufactured as a saferreplacement for the now-banned DDT, alters the estrogen-regulated geneHoxa10 in the reproductive tract and reduces the ability of the uterusto support embryo implantation. The researchers used mice and thenhuman cell lines to confirm their findings.

MXC is a man-made pesticide used to kill flies, mosquitoes,cockroaches and other insects, and is applied directly to food crops,livestock, home gardens and pets. It is one of a large number ofchemicals that can mimic the action of hormones and in some instancesinterfere with endocrine function.

Some of these endocrine disruptors bind estrogen receptors andadversely affect reproductive tract development, which is heavilyinfluenced by estrogen. MXC and other chemicals like DDT have beenshown in other studies to induce abnormalities in tissue developmentand function in the female reproductive tract.

"MXC has an adverse effect on these mice similar to that ofDES, a synthetic estrogen," said senior author Hugh S. Taylor, M.D.,associate professor in the Division of Reproductive Endocrinology andInfertility in the Department of Obstetrics, Gynecology &Reproductive Sciences at Yale School of Medicine. "Female offspring ofwomen exposed to DES were more likely to have an abnormally shapedcervix, were more prone to cancer of the vagina, miscarriages, earlylabor and other complications."

Other authors on the study included Xiaolan Fei and Hajin Chung

###

Citation: Endocrinology, 146: 3445-3451 (August 2005)


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Common Pesticide May Reduce Fertility In Women." ScienceDaily. ScienceDaily, 12 September 2005. <www.sciencedaily.com/releases/2005/09/050912124225.htm>.
Yale University. (2005, September 12). Common Pesticide May Reduce Fertility In Women. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2005/09/050912124225.htm
Yale University. "Common Pesticide May Reduce Fertility In Women." ScienceDaily. www.sciencedaily.com/releases/2005/09/050912124225.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins