Featured Research

from universities, journals, and other organizations

Treatment Shows Long-term Benefits For Cystic Fibrosis Patients

Date:
January 23, 2006
Source:
NIH/National Heart, Lung, and Blood Institute
Summary:
New research suggests that inhaling hypertonic saline, a water-based concentrated salt solution, could provide long-term benefits for lung health in patients with cystic fibrosis (CF). Researchers tested the effects of inhaling the saline four times daily for 14 days in 24 patients with CF. The treatment significantly improved mucus clearance, lung function, and breathing symptoms. The journal also includes a report by Australian researchers about a larger, longer study, as well as an editorial.

New research suggests that inhaling hypertonic saline, a water-based concentrated salt solution, could provide long-term benefits for lung health in patients with cystic fibrosis (CF). Researchers at the University of North Carolina (UNC) at Chapel Hill tested the effects of inhaling the saline four times daily for 14 days in 24 older patients with CF (ages 14 years or older). The treatment significantly improved mucus clearance, lung function, and breathing symptoms. If confirmed, the findings could lead to a new and inexpensive treatment for CF. The study was funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) and by the Cystic Fibrosis Foundation.

Related Articles


"Sustained Improvement in Mucus Clearance and Lung Function in Cystic Fibrosis with Hypertonic Saline" will be published in the January 19 issue of the New England Journal of Medicine (NEJM). This week's NEJM also includes a report by Australian researchers who followed 164 patients receiving a similar treatment for nearly one year, as well as an editorial about the two studies.

CF is a chronic, progressive, and frequently fatal genetic disease that affects about 30,000 children and young adults in the United States. The UNC researchers believe that the concentrated saline increases mucus volume, which helps the airways to clear bacteria and inhaled debris and could limit the number and severity of lung infections. Repeated infections are thought to contribute to lung damage over time. The study results could be particularly important if future research shows that the treatment similarly benefits infants and young children and could ultimately prevent or delay lung damage. Respiratory failure is the most common cause of death in CF patients.

###

NHLBI is part of the National Institutes of Health (NIH), the Federal Government's primary agency for biomedical and behavioral research. NIH is a component of the U.S. Department of Health and Human Services. NHLBI press releases and fact sheets, including information on cystic fibrosis, is available at www.nhlbi.nih.gov.


Story Source:

The above story is based on materials provided by NIH/National Heart, Lung, and Blood Institute. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Heart, Lung, and Blood Institute. "Treatment Shows Long-term Benefits For Cystic Fibrosis Patients." ScienceDaily. ScienceDaily, 23 January 2006. <www.sciencedaily.com/releases/2006/01/060123123231.htm>.
NIH/National Heart, Lung, and Blood Institute. (2006, January 23). Treatment Shows Long-term Benefits For Cystic Fibrosis Patients. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2006/01/060123123231.htm
NIH/National Heart, Lung, and Blood Institute. "Treatment Shows Long-term Benefits For Cystic Fibrosis Patients." ScienceDaily. www.sciencedaily.com/releases/2006/01/060123123231.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins