Nov. 14, 2022 Researchers have developed a simple urine test to measure the severity of the serious disease cystic fibrosis and assess the effect of new ...
Oct. 25, 2022 Cystic fibrosis is missed more often in newborn screenings for non-white than white babies, creating higher risk for irreversible lung damage and other serious outcomes in Black, Hispanic, Asian, ...
Sep. 29, 2022 Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study ...
Aug. 1, 2022 Cystic fibrosis (CF) is caused by a mutation of the CFTR gene. While there are many hundreds of known mutations, not all of them are currently treatable which means a significant number of CF ...
July 27, 2022 Infants from minoritized racial and ethnic backgrounds who have positive newborn screening tests for cystic fibrosis received their diagnostic follow-up for the disease later than recommended and ...
July 14, 2022 Antisense oligonucleotides, or ASOs, are molecules that can be used to control protein levels in cells. Scientists have discovered a new way ASOs may help cells produce a protein missing in cystic ...
June 16, 2022 A drug discovery approach developed -- in part inspired by oil companies -- revealed why drugs for cystic fibrosis fall ...
May 24, 2022 Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure. It is caused by ...
Feb. 14, 2022 Researchers have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current ...
Jan. 24, 2022 Protein folding diseases, from Alzheimer's to Gaucher's, may one day be treated by a unique class of protein corrector molecules that are already helping manage cystic ...
Nov. 19, 2021 Despite advances in patient screenings and breakthrough therapies that allow CF patients now to live into their mid- to late 30s or 40s, sometimes even longer, all patients are plagued by bacteria ...
Oct. 21, 2021 In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of ...
Oct. 19, 2021 A dogma-challenging discovery reveals that highly adapted bacterial communities in the sinuses of people with cystic fibrosis become more fragmented and experience mutations that erode their genomes. ...
Oct. 6, 2021 New understanding of cellular defects related to Cystic Fibrosis (CF) could help pave the way for ...
Aug. 9, 2021 Researchers corrected mutations that cause cystic fibrosis in cultured human stem cells. They used a technique called prime editing to replace the 'faulty' piece of DNA with a healthy ...
July 19, 2021 An experimental drug suggests that a 'path is clearly achievable' to treat currently untreatable cases of cystic fibrosis disease caused by nonsense mutations. This includes about 11 ...
June 16, 2021 A new CF treatment strategy involves small, nucleic acid molecules called oligonucleotides that can correct some of the gene defects that underlie CF but are not addressed by existing modulator ...
May 14, 2021 New nanotechnology could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, ...
May 6, 2021 A team of researchers has developed a molecular catalog of cells in healthy lungs and the lungs of people with cystic ...
Apr. 29, 2021 Scientists have been able to track how a multi-drug resistant organism is able to evolve and spread widely among cystic fibrosis patients - showing that it can evolve rapidly within an individual ...