Featured Research

from universities, journals, and other organizations

New Clinical Trial Seeks To Find Better Ways Of Treating Uterine Fibroids

Date:
May 27, 2006
Source:
University of Pennsylvania School of Medicine
Summary:
Researchers at the University of Pennsylvania School of Medicine are working on ways to improve the results of a non-surgical method to treat fibroids. They are examining the overall effectiveness of different agents used to destroy uterine fibroids - a discovery that could lead to more answers about the durability of a procedure called Uterine Fibroid Embolization (UFE).

Researchers at the University of Pennsylvania School of Medicine are working on ways to improve the results of a non-surgical method to treat fibroids. They are examining the overall effectiveness of different agents used to destroy uterine fibroids - a discovery that could lead to more answers about the durability of a procedure called Uterine Fibroid Embolization (UFE). It's already been established throughout the medical community that, after a decade, UFE works to relieve the symptoms of fibroids. Now, in this new study, investigators want to learn how to optimize the procedure, by running a comparison of materials used during it.

Related Articles


"We already know that UFE has an 85-90% success rate, offering less complications and a shorter recovery time than surgical options," Richard Shlansky-Goldberg, MD, Interventional Radiologist at Penn and Principal Investigator of this study, explains, "So in 2006, the question becomes, now that we know the procedure is effective and durable, 'Which product would be better?'"

Uterine fibroids are benign (non-cancerous) tumors of the uterus that affect an estimated 20-40% of women, and for many, cause symptoms disrupting the quality of their lives. Uterine Fibroids affect more than six million women in the U.S. each year. The exact reason uterine fibroids (the most common type of abnormal growth in the uterus) develop is unknown, but medical researchers have associated the condition with genetics and hormones. If left untreated, uterine fibroids can cause infertility.

The treatment for uterine fibroids depends upon the size and location of the fibroids and the severity of symptoms. Uterine fibroid embolization (UFE), also known as uterine artery embolization (UAE), is a minimally invasive alternative to a hysterectomy and is a proven way to treat fibroids and relieve its symptoms of heavy bleeding, pressure, pain, and excessive urination.

Interventional radiologists don't actually remove the fibroids during the UFE procedure. They shut them down and gradually shrink them, by blocking the blood supply to the fibroids. They do this by using a catheter to inject embolic agents (tiny plastic or sponge-like particles) into the artery, to "dam up" the blood flow to the fibroids.

During this trial at Penn, several researchers will utilize two different embolic agents, comparing the outcomes in patients. 24 hours after each procedure, they will conduct an MRI to see how much fibroid tissue is destroyed. They'll look again, when the patient leaves the hospital. Shlansky-Goldberg adds, "We hope to answer two questions. One - In looking at the different outcomes of each particle, does one do a more effective job of eliminating fibroids? And two -- What does the uterus look like immediately after the UFE procedure and then later, after three months?"

This is a randomized, single-center study comparing Contour SE Microspheres to Embosphere Microspheres for treating symptomatic uterine fibroids with UFE. The head-to-head study at Penn, funded by Boston Scientific, will involve 60 patients. Penn is still enrolling patients in the study.

The clinical trial is expected to last about nine months.


Story Source:

The above story is based on materials provided by University of Pennsylvania School of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

University of Pennsylvania School of Medicine. "New Clinical Trial Seeks To Find Better Ways Of Treating Uterine Fibroids." ScienceDaily. ScienceDaily, 27 May 2006. <www.sciencedaily.com/releases/2006/05/060527094313.htm>.
University of Pennsylvania School of Medicine. (2006, May 27). New Clinical Trial Seeks To Find Better Ways Of Treating Uterine Fibroids. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2006/05/060527094313.htm
University of Pennsylvania School of Medicine. "New Clinical Trial Seeks To Find Better Ways Of Treating Uterine Fibroids." ScienceDaily. www.sciencedaily.com/releases/2006/05/060527094313.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins