Featured Research

from universities, journals, and other organizations

Bioengineered Tissue Implants Regenerate Damaged Knee Cartilage

Date:
July 5, 2006
Source:
University of Bristol
Summary:
Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.

Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.

The study, "Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees", published in the July 2006 (Volume 12, Number 7) issue of Tissue Engineering, demonstrates that engineered cartilage tissue can grow and mature when implanted into patients with a knee injury. The novel tissue engineering approach can lead to cartilage regeneration even in knees affected by osteoarthritis.

The tissue engineering method used in this study involved isolating cells from healthy cartilage removed during surgery from 23 patients with an average age of 36 years. After growing the cells in culture for 14 days, the researchers seeded them onto scaffolds made of esterified hyaluronic acid, grew them for another 14 days on the scaffolds, and then implanted them into the injured knees of the study patients.

Cartilage regeneration was seen in ten of 23 patients, including in some patients with pre-existing early osteoarthritis of the knee secondary to traumatic injury. Maturation of the implanted, tissue-engineered cartilage was evident as early as 11 months after implantation.

Antony Hollander, ARC Professor of Rheumatology & Tissue Engineering at Bristol University who led the study, said: "This is the first time we have shown that tissue-engineered cartilage implanted into knees can mature within 12 months after implantation, even in joints showing signs of osteoarthritis.

"Left untreated, many cartilage injuries will progress to osteoarthritis and the need for eventual replacement of the whole joint. Future investigations need to be carried out but this approach will allow us to improve further the outcome of cartilage repair."


Story Source:

The above story is based on materials provided by University of Bristol. Note: Materials may be edited for content and length.


Cite This Page:

University of Bristol. "Bioengineered Tissue Implants Regenerate Damaged Knee Cartilage." ScienceDaily. ScienceDaily, 5 July 2006. <www.sciencedaily.com/releases/2006/07/060705082457.htm>.
University of Bristol. (2006, July 5). Bioengineered Tissue Implants Regenerate Damaged Knee Cartilage. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2006/07/060705082457.htm
University of Bristol. "Bioengineered Tissue Implants Regenerate Damaged Knee Cartilage." ScienceDaily. www.sciencedaily.com/releases/2006/07/060705082457.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins