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Biotechs Expand Into Small Molecules For Drug Discovery

Date:
October 31, 2006
Source:
American Chemical Society
Summary:
Biotech companies traditionally focus on large proteins in their quest to find new drugs. But faced with the complex nature of disease, these companies are increasingly turning to small molecules as well. This new push into small-molecule drug design, which researchers hope will deliver better and more effective disease treatments, is explored in a report scheduled for the Oct. 30 issue of Chemical & Engineering News, the ACS's weekly newsmagazine.

Biotech companies traditionally focus on large proteins in their quest to find new drugs. But faced with the complex nature of disease, these companies are increasingly turning to small molecules as well.

This new push into small-molecule drug design, which researchers hope will deliver better and more effective disease treatments, is explored in a report scheduled for the Oct. 30 issue of Chemical & Engineering News, the ACS's weekly newsmagazine.

Associate Editor Lisa M. Jarvis describes how major biotech companies such as Genentech and Amgen have moved into the small-molecule arena and expanded their chemistry operations in the process, including new partnerships with drug discovery firms. These efforts have increasingly brought together chemists from a wide range of disciplines, including medicinal, computational and process chemistry, Jarvis writes.

Biotech's investment in small-molecule research is starting to pay off in the form of new drugs, she notes. A few companies already have commercialized new small-molecule drugs for the treatment of lung cancer and kidney disease, while drugs for multiple sclerosis, Parkinson's and other diseases are making their way through the pipeline.

By combining small-molecule approaches with protein research, biotech companies are boosting their odds of producing more effective treatments for some of our most challenging diseases, according to the article.


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The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Biotechs Expand Into Small Molecules For Drug Discovery." ScienceDaily. ScienceDaily, 31 October 2006. <www.sciencedaily.com/releases/2006/10/061030120854.htm>.
American Chemical Society. (2006, October 31). Biotechs Expand Into Small Molecules For Drug Discovery. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2006/10/061030120854.htm
American Chemical Society. "Biotechs Expand Into Small Molecules For Drug Discovery." ScienceDaily. www.sciencedaily.com/releases/2006/10/061030120854.htm (accessed October 1, 2014).

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