Featured Research

from universities, journals, and other organizations

Report Calls For Using Heated Chemotherapy After Colon Cancer Surgery To Optimize Patient Survival

Date:
November 6, 2006
Source:
Weill Cornell Medical College
Summary:
There is new hope for some of the most seriously ill colon cancer patients today, following the release of a consensus statement by 72 leading oncology surgeons from 14 countries, including the United States. The Peritoneal Surface Malignancy Group (PSMG) has concluded that surgery, followed by heated chemotherapy delivered through the lower abdomen of the patient before leaving the operating room, may significantly increase the life expectancy for patients with Stage IV colorectal cancer.

There is new hope for some of the most seriously ill colon cancer patients today, following the release of a consensus statement by 72 leading oncology surgeons from 14 countries, including the United States. The Peritoneal Surface Malignancy Group (PSMG), including doctors from the University of Pittsburgh Medical Center, Baylor University Medical Center in Dallas; H. Lee Moffitt Cancer Center in Tampa; Walter Reed Army Medical Center in Washington; and St. Agnes Hospital in Baltimore, has concluded that surgery, followed by heated chemotherapy delivered through the lower abdomen of the patient before leaving the operating room, may significantly increase the life expectancy for patients with Stage IV colorectal cancer.

Related Articles


The heated chemotherapy is designed to help reliably attack any residual cancer cells remaining after surgery. The consensus statement: "Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Management of Peritoneal Surface Malignancies of Colonic Origin", appears on the Web site for the Annals of Surgical Oncology.

HIPEC involves the use of conventional chemotherapy drugs heated to such a high temperature as to kill cancer cells. Additionally, by bathing the abdomen with heated chemotherapy immediately following surgery, a higher dose of medication can be used than would normally be tolerated by a patient if given intravenously -- the traditional way chemotherapy is administered. Before releasing today's consensus statement, the PSMG reviewed several peer-reviewed clinical articles published by nationally renowned oncology researchers and surgeons to establish standardized methods to deliver HIPEC; define patient selection criteria; and improve surgical techniques.

In 2005, an estimated 145,000 new cases of colorectal cancer were diagnosed in the United States, according to the American Cancer Society. Doctors estimate 30 percent of these patients would benefit from surgery with HIPEC. The published data on the treatment of patients with Stage IV colorectal cancer, with combinations of tumor removal surgery and chemotherapy, showed a median survival of greater than 20 months, compared to six-month survival with traditional intravenous chemotherapy alone.

"HIPEC is an aggressive surgical treatment for end-stage cancer patients, with promising results," says Jesus Esquivel, M.D., lead author of the consensus statement and director of the peritoneal surface malignancy program at St. Agnes Healthcare in Baltimore. "This innovative therapy, with surgery, is helping to significantly improve, and extend the lives of patients who are in desperate need."

Patients whose colon cancer recurs, and those with cancer that has spread to other parts of the body, involving the abdomen or peritoneal cavity, are the patients who benefited most from the combination of surgery followed by HIPEC. Although not addressed in the consensus statement, surgical oncologists are utilizing the treatment for patients with other forms of abdominal cancers, including pancreatic, ovarian, and gastric cancer.

The PSMG is currently 72 national and international surgical oncologists from 55 cancer centers in 14 countries, who are dedicated to education, research, and improved care for patients with advanced abdominal cancers.


Story Source:

The above story is based on materials provided by Weill Cornell Medical College. Note: Materials may be edited for content and length.


Cite This Page:

Weill Cornell Medical College. "Report Calls For Using Heated Chemotherapy After Colon Cancer Surgery To Optimize Patient Survival." ScienceDaily. ScienceDaily, 6 November 2006. <www.sciencedaily.com/releases/2006/11/061103104037.htm>.
Weill Cornell Medical College. (2006, November 6). Report Calls For Using Heated Chemotherapy After Colon Cancer Surgery To Optimize Patient Survival. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2006/11/061103104037.htm
Weill Cornell Medical College. "Report Calls For Using Heated Chemotherapy After Colon Cancer Surgery To Optimize Patient Survival." ScienceDaily. www.sciencedaily.com/releases/2006/11/061103104037.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins