Featured Research

from universities, journals, and other organizations

Preventing Costly Missteps In Drug Development

Date:
November 7, 2006
Source:
American Chemical Society
Summary:
The script for one of the most dreaded scenarios in new drug development reads like this: Company A sinks several hundred million dollars into putting a new drug onto pharmacy shelves. Only then do serious side effects appear, and force withdrawal of that drug from the market. Researchers in India now are reporting development of a new and more accurate method for predicting toxicity in the very early stages of drug development.

The script for one of the most dreaded scenarios in new drug development reads like this: Company A sinks several hundred million dollars into putting a new drug onto pharmacy shelves. Only then do serious side effects appear, and force withdrawal of that drug from the market.

Related Articles


Researchers in India now are reporting development of a new and more accurate method for predicting toxicity in the very early stages of drug development.

Nagasuma R. Chandra and colleagues describe the computer technique in the November/December issue of the ACS's bi-monthly Journal of Chemical Information and Modeling. They also report on its use in predicting with high accuracy one form of toxicity - a heart rhythm disorder that forced withdrawal of the popular antihistamine terfenadine (Seldane).

The technique identifies patterns in the substructure of a drug's molecular structure that can raise red flags over hidden toxicity.

"Such screening saves a lot of time, effort, and money and helps in better planning and focusing of the available resources for drug discovery," they write.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Preventing Costly Missteps In Drug Development." ScienceDaily. ScienceDaily, 7 November 2006. <www.sciencedaily.com/releases/2006/11/061106095518.htm>.
American Chemical Society. (2006, November 7). Preventing Costly Missteps In Drug Development. ScienceDaily. Retrieved March 28, 2015 from www.sciencedaily.com/releases/2006/11/061106095518.htm
American Chemical Society. "Preventing Costly Missteps In Drug Development." ScienceDaily. www.sciencedaily.com/releases/2006/11/061106095518.htm (accessed March 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, March 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins