Featured Research

from universities, journals, and other organizations

Sports Cheats Beware -- New Test Detects Previously Undetectable Drug

Date:
November 13, 2006
Source:
John Wiley & Sons, Inc.
Summary:
Injecting performance enhancing corticosteroid hormones for other than medical treatment is banned, and tests exist that can detect injected hormones. Injecting synacthen, which stimulates the body to produce extra amounts of its own corticosteroid hormones is also banned. But until now there has been no test that could detect it in a blood sample.

Injecting performance enhancing corticosteroid hormones for other than medical treatment is banned, and tests exist that can detect injected hormones. Injecting synacthen, which stimulates the body to produce extra amounts of its own corticosteroid hormones is also banned. But until now there has been no test that could detect it in a blood sample.

That has just changed. Research published this week in Rapid Communications in Mass Spectrometry describes a method that can detect synacthen, even though it will only be found in incredibly low concentrations in a person's blood sample.

Synacthen is a protein, and scientists have developed a method that can specifically search for the minute traces of synacthen in a blood sample. Called immunological purification, this technique can find any synacthen molecules even though its concentration is 10,000,000 less than other proteins in blood plasma.

There are severe penalties for any person caught taking banned drugs. It is therefore very important that any test is able to be certain about its statement that a particular molecule is present -- in this case synacthen. To confirm that the immunological purification has pulled out synacthen, the protein is then subjected to a further two-stage test -- chromatography separation and mass spectrometric analysis. This lets scientists produce a chemical fingerprint of the molecule -- a fingerprint that uniquely identifies it.

"If the drug testing authorities adopt this new test it will close a gap in the current drug testing system, and mean that athletes will no longer be able to get away with this form of cheating," says lead author Mario Thevis, who works in the Center for Preventive Doping Research -- Institute of Biochemistry, at the German Sport University Cologne in Germany.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Sports Cheats Beware -- New Test Detects Previously Undetectable Drug." ScienceDaily. ScienceDaily, 13 November 2006. <www.sciencedaily.com/releases/2006/11/061112234802.htm>.
John Wiley & Sons, Inc.. (2006, November 13). Sports Cheats Beware -- New Test Detects Previously Undetectable Drug. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2006/11/061112234802.htm
John Wiley & Sons, Inc.. "Sports Cheats Beware -- New Test Detects Previously Undetectable Drug." ScienceDaily. www.sciencedaily.com/releases/2006/11/061112234802.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins