Featured Research

from universities, journals, and other organizations

Sports Cheats Beware -- New Test Detects Previously Undetectable Drug

Date:
November 13, 2006
Source:
John Wiley & Sons, Inc.
Summary:
Injecting performance enhancing corticosteroid hormones for other than medical treatment is banned, and tests exist that can detect injected hormones. Injecting synacthen, which stimulates the body to produce extra amounts of its own corticosteroid hormones is also banned. But until now there has been no test that could detect it in a blood sample.

Injecting performance enhancing corticosteroid hormones for other than medical treatment is banned, and tests exist that can detect injected hormones. Injecting synacthen, which stimulates the body to produce extra amounts of its own corticosteroid hormones is also banned. But until now there has been no test that could detect it in a blood sample.

That has just changed. Research published this week in Rapid Communications in Mass Spectrometry describes a method that can detect synacthen, even though it will only be found in incredibly low concentrations in a person's blood sample.

Synacthen is a protein, and scientists have developed a method that can specifically search for the minute traces of synacthen in a blood sample. Called immunological purification, this technique can find any synacthen molecules even though its concentration is 10,000,000 less than other proteins in blood plasma.

There are severe penalties for any person caught taking banned drugs. It is therefore very important that any test is able to be certain about its statement that a particular molecule is present -- in this case synacthen. To confirm that the immunological purification has pulled out synacthen, the protein is then subjected to a further two-stage test -- chromatography separation and mass spectrometric analysis. This lets scientists produce a chemical fingerprint of the molecule -- a fingerprint that uniquely identifies it.

"If the drug testing authorities adopt this new test it will close a gap in the current drug testing system, and mean that athletes will no longer be able to get away with this form of cheating," says lead author Mario Thevis, who works in the Center for Preventive Doping Research -- Institute of Biochemistry, at the German Sport University Cologne in Germany.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Sports Cheats Beware -- New Test Detects Previously Undetectable Drug." ScienceDaily. ScienceDaily, 13 November 2006. <www.sciencedaily.com/releases/2006/11/061112234802.htm>.
John Wiley & Sons, Inc.. (2006, November 13). Sports Cheats Beware -- New Test Detects Previously Undetectable Drug. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2006/11/061112234802.htm
John Wiley & Sons, Inc.. "Sports Cheats Beware -- New Test Detects Previously Undetectable Drug." ScienceDaily. www.sciencedaily.com/releases/2006/11/061112234802.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins