Featured Research

from universities, journals, and other organizations

Low-cost Parkinson's Disease Diagnostic Test A World First

Date:
February 24, 2007
Source:
Howard Florey Institute
Summary:
Scientists at Melbourne's Howard Florey Institute have developed a cost-effective diagnostic test for Parkinson's disease (PD), which will also assist researchers to understand the genetic basis of PD and to undertake large-scale studies to identify the genes that cause this debilitating condition.

Scientists at Melbourne 's Howard Florey Institute have developed a cost-effective diagnostic test for Parkinson's disease (PD), which will also assist researchers to understand the genetic basis of PD and to undertake large-scale studies to identify the genes that cause this debilitating condition.

Related Articles


Currently there is no specific PD diagnostic test and doctors rely on their observations to make a diagnosis, which means some patients may not be prescribed the most suitable medication and around 15% of those diagnosed may actually be suffering from something else.

Whilst conventional DNA sequencing of all six known Parkinson's disease genes is available, this test costs $4,000 and is not covered by Medicare.

Florey research leader, Dr Justin Rubio, has created a ' gene-sequencing chip' that screens 17 genes in all, including the six known Parkinson's disease genes plus some other suspects in one simple test, at a cost of $500.

Dr Rubio said the gene-sequencing chip would allow for routine testing of people suspected of having Parkinson's disease.

"Around 100,000 Australians have Parkinson's disease but few have had DNA testing for the known genes that cause the disease due to the prohibitive cost," Dr Rubio said.

"We are now seeking funding to conduct a large-scale trial to examine the effectiveness of our $500 chip compared with the $4,000 DNA test and we are confident our chip will prove to be the better option.

"In addition to providing a genetic diagnosis it is hoped that our chip will eventually be able to pinpoint genetic changes that help to predict a person's prognosis and even the treatment that best suits them.

"As the test is relatively cheap and only involves collecting a sample of blood or saliva, it could also be made available to the patient's relatives and those at risk of developing PD.

"In addition to being a diagnostic tool, this low-cost chip will allow researchers to undertake an Australia-wide gene-mapping study to identify further genes that are involved in PD.

"More genetic information will deepen our understanding of PD and enable researchers to work towards ways of preventing and treating the disease.

"The successful implementation of this technology could also lead to genetic testing for other diseases ," Dr Rubio said.

Dr Rubio plans to test the chip on DNA samples from 400 people with PD who were recruited from Victoria and Tasmania, and this project involves collaborators from hospitals and research institutes in both states.

Using the gene-sequencing chip, Dr Rubio and his collaborators now hope to extend the 'Gene Discovery' project to all Australian states to determine the genetic basis of PD.


Story Source:

The above story is based on materials provided by Howard Florey Institute. Note: Materials may be edited for content and length.


Cite This Page:

Howard Florey Institute. "Low-cost Parkinson's Disease Diagnostic Test A World First." ScienceDaily. ScienceDaily, 24 February 2007. <www.sciencedaily.com/releases/2007/02/070223143534.htm>.
Howard Florey Institute. (2007, February 24). Low-cost Parkinson's Disease Diagnostic Test A World First. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2007/02/070223143534.htm
Howard Florey Institute. "Low-cost Parkinson's Disease Diagnostic Test A World First." ScienceDaily. www.sciencedaily.com/releases/2007/02/070223143534.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins