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Study Shows That Anal Cytology Predicts Anal Precancer In HIV-positive Gay Men

Date:
March 31, 2007
Source:
University of California - Los Angeles
Summary:
HIV-positive men who have sex with men are up to 90 times more likely than the general population to develop anal cancer. Detection of precancerous changes (anal dysplasia) by anal cytology -- essentially an anal canal Pap smear -- is a relatively new procedure and one that has yet to enter standard practice. This UCLA study demonstrated that abnormal anal cytology was highly predictive of anal cell abnormalities that were subsequently confirmed by anal biopsy.

HIV-positive men who have sex with men are up to 90 times more likely than the general population to develop anal cancer. Detection of precancerous changes (anal dysplasia) by anal cytology -- essentially an anal canal Pap smear -- is a relatively new procedure and one that has yet to enter standard practice.

Now researchers at UCLA report in a new study that they have demonstrated that abnormal anal cytology was highly predictive of anal cell abnormalities that were subsequently confirmed by anal biopsy. The study was based on data from 244 patients at the UCLA CARE clinic who had anal cytology screenings between February 2002 and December 2004.

Abnormal anal cytology in HIV-positive men who have sex with men is highly indicative of the presence of abnormal anal cells that may be precancerous and should prompt further investigation. The UCLA CARE Center is one of a handful of clinics in the United States offering an anal dysplasia screening and management service.

Authors of the study include Ross D. Cranston, Steven.D. Hart , Jeffrey A. Gornbein, Sharon L. Hirschowitz, Galen Cortina, and Ardis.A. Moe, all of UCLA. The research appears in the February issue of the International Journal of STD & AIDS.


Story Source:

The above story is based on materials provided by University of California - Los Angeles. Note: Materials may be edited for content and length.


Cite This Page:

University of California - Los Angeles. "Study Shows That Anal Cytology Predicts Anal Precancer In HIV-positive Gay Men." ScienceDaily. ScienceDaily, 31 March 2007. <www.sciencedaily.com/releases/2007/03/070321181247.htm>.
University of California - Los Angeles. (2007, March 31). Study Shows That Anal Cytology Predicts Anal Precancer In HIV-positive Gay Men. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2007/03/070321181247.htm
University of California - Los Angeles. "Study Shows That Anal Cytology Predicts Anal Precancer In HIV-positive Gay Men." ScienceDaily. www.sciencedaily.com/releases/2007/03/070321181247.htm (accessed September 30, 2014).

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