Featured Research

from universities, journals, and other organizations

Using Saliva To Diagnose Primary Sjögren's Syndrome

Date:
March 26, 2007
Source:
International & American Association for Dental Research
Summary:
Scientists are reporting that, instead of blood tests and biopsy, saliva can be used to detect primary Sjögren's Syndrome (pSS), an autoimmune disease which affects approximately 4 million American, 90 percent being women.

Scientists are reporting that, instead of blood tests and biopsy, saliva can be used to detect primary Sjögren's Syndrome (pSS), an autoimmune disease which affects  approximately 4 million American, 90% being women. pSS patients are 40 times more at risk than healthy people to develop lymphoma, a fatal lymphocytic cancer.

Related Articles


Scientists at the University of California-Los Angeles have identified a panel of salivary biomarkers that can distinguish pSS patients from healthy subjects. Using cutting-edge proteomics and genomics technologies, they searched globally for markers in saliva from SS patients and healthy people, and found that saliva, especially whole saliva (that is, the combined saliva in the mouth, vs. saliva from the individual salivary glands), is informative for detecting patients with pSS.

In addition, the proteomic and genomic profile of these markers reflects the damage to glandular cells, activated anti-viral immune response, or programmed cell death known to be involved in SS pathogenesis. The value of these candidate biomarkers for SS diagnosis has been confirmed by independent technologies. The saliva proteomic and genomic biomarkers collectively will have a positive beneficial diagnostic value on the clinical detection of pSS in the near future.

This is a summary of abstract #192, "Saliva RNA Biomarker Candidates for Primary Sjögren's Syndrome Detection", by J. Wang et al., of the University of California-Los Angeles, to be presented during the 85th General Session of the International Association for Dental Research.


Story Source:

The above story is based on materials provided by International & American Association for Dental Research. Note: Materials may be edited for content and length.


Cite This Page:

International & American Association for Dental Research. "Using Saliva To Diagnose Primary Sjögren's Syndrome." ScienceDaily. ScienceDaily, 26 March 2007. <www.sciencedaily.com/releases/2007/03/070322105424.htm>.
International & American Association for Dental Research. (2007, March 26). Using Saliva To Diagnose Primary Sjögren's Syndrome. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2007/03/070322105424.htm
International & American Association for Dental Research. "Using Saliva To Diagnose Primary Sjögren's Syndrome." ScienceDaily. www.sciencedaily.com/releases/2007/03/070322105424.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) — The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) — President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) — The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) — The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins