Featured Research

from universities, journals, and other organizations

Worldwide AIDS Initiative: Developing A Quick Immune System Test

Date:
April 9, 2007
Source:
Rush University Medical Center
Summary:
Researchers are working to develop a simple, affordable and rapid test to measure the immune systems of people infected with HIV/AIDS in developing countries.

Researchers at Rush University Medical Center have been selected to participate in a collaborative initiative to develop a simple, affordable and rapid test to measure the immune systems of people infected with HIV/AIDS in developing countries. The four year CD4 Initiative is conducted under the leadership of Imperial College London with funding from the Bill & Melinda Gates Foundation.

Related Articles


The CD4 Initiative will develop an easy to use device that can measure CD4+ T-lymphocytes in HIV+ patients. The CD4 cell count measures the number of these critical disease-fighting cells in the blood, a figure that health care workers need in order to make key clinical decisions in managing HIV disease, such as when to begin or to switch antiretroviral therapy.

Study co-investigator Alan Landay, PhD, chairman of the department of Immunology and Microbiology at Rush, said current technologies for measuring CD4 counts are expensive to buy and maintain, and require a level of infrastructure and training thatis often not available in many developing countries.

“In remote villages where there are likely to be no laboratory facilities, health care workers need a simple point-of-care test they can perform with little training,” said Landay. “The goal is an inexpensive test that can use blood from a simple finger prick and requires no sample processing or microscopy.”

Landay will collaborate with scientists at the Burnet Institute in Melbourne, Australia. The technology underpinning this test was developed by associate professor David Anderson, a co-investigator on this grant and deputy director at the Burnet Institute. The principal investigator on the proposal is Suzanne Crowe, head of the Pathogenesis and Clinical Research Program at the Burnet Institute. Other co-investigators include Professor Tom Denny of Duke University School of Medicine.

The initiative will take a project management approach using multiple research teams around the world from academia, private companies and other institutions that will work collaboratively under the leadership of Imperial College London.

“Despite the burden of HIV/AIDS on the developing worlds, many of the diagnostic tools are just not accessible there due to the high cost and complexity of use. This initiative will help develop new, simple, rapid, robust and affordable tools and help remove one important barrier to the effective implementation of AIDS care in these countries,” said professor Stephen Smith, principal of the faculty of medicine at Imperial College London.

Initial funding for the proof of concept was provided by a grant from the Doris Duke Foundation.


Story Source:

The above story is based on materials provided by Rush University Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Rush University Medical Center. "Worldwide AIDS Initiative: Developing A Quick Immune System Test." ScienceDaily. ScienceDaily, 9 April 2007. <www.sciencedaily.com/releases/2007/04/070402153157.htm>.
Rush University Medical Center. (2007, April 9). Worldwide AIDS Initiative: Developing A Quick Immune System Test. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2007/04/070402153157.htm
Rush University Medical Center. "Worldwide AIDS Initiative: Developing A Quick Immune System Test." ScienceDaily. www.sciencedaily.com/releases/2007/04/070402153157.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins