Featured Research

from universities, journals, and other organizations

Antihistamine Offers Relief For Cirrhosis Patients With Insomnia

Date:
May 28, 2007
Source:
Blackwell Publishing
Summary:
A common medication used by allergy sufferers may offer relief to cirrhosis patients that suffer from insomnia. A new study shows that the antihistamine hydroxyzine is an effective treatment for restoring normal sleep patterns when liver damage causes chemical pathways in the brain to be disrupted.

A common medication used by allergy sufferers may offer relief to cirrhosis patients that suffer from insomnia. A new study in The American Journal of Gastroenterology shows that the antihistamine hydroxyzine is an effective treatment for restoring normal sleep patterns when liver damage causes chemical pathways in the brain to be disrupted.

“In patients with cirrhosis of the liver, histamine levels in the brain can be altered,” says study author Dr. Laurent Spahr. “In the brain, histamine regulates the sleep-wake cycle, so if levels of this chemical get out of balance, so do sleep patterns.” In this study, 65 percent of the patients receiving hydroxyzine before bedtime experienced improved sleep quality.

Dr. Spahr says that hydroxyzine is a welcome alternative to ‘classical’ sleeping pills, as they are usually ineffective and can lead to serious side effects in cirrhosis patients, such as coma. Recent practice guidelines forbid the use of these ‘classical’ drugs for cirrhosis patients, declaring them too dangerous.

According to Dr. Spahr, however, hydroxyzine is not risk-free. “This medication must be used with caution. Patients must be monitored carefully by a physician for their particular response to the drug, and should be taken off the medication if there are any signs of trouble.”


Story Source:

The above story is based on materials provided by Blackwell Publishing. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing. "Antihistamine Offers Relief For Cirrhosis Patients With Insomnia." ScienceDaily. ScienceDaily, 28 May 2007. <www.sciencedaily.com/releases/2007/05/070527100414.htm>.
Blackwell Publishing. (2007, May 28). Antihistamine Offers Relief For Cirrhosis Patients With Insomnia. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2007/05/070527100414.htm
Blackwell Publishing. "Antihistamine Offers Relief For Cirrhosis Patients With Insomnia." ScienceDaily. www.sciencedaily.com/releases/2007/05/070527100414.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins