Featured Research

from universities, journals, and other organizations

Antihistamine Offers Relief For Cirrhosis Patients With Insomnia

Date:
May 28, 2007
Source:
Blackwell Publishing
Summary:
A common medication used by allergy sufferers may offer relief to cirrhosis patients that suffer from insomnia. A new study shows that the antihistamine hydroxyzine is an effective treatment for restoring normal sleep patterns when liver damage causes chemical pathways in the brain to be disrupted.

A common medication used by allergy sufferers may offer relief to cirrhosis patients that suffer from insomnia. A new study in The American Journal of Gastroenterology shows that the antihistamine hydroxyzine is an effective treatment for restoring normal sleep patterns when liver damage causes chemical pathways in the brain to be disrupted.

Related Articles


“In patients with cirrhosis of the liver, histamine levels in the brain can be altered,” says study author Dr. Laurent Spahr. “In the brain, histamine regulates the sleep-wake cycle, so if levels of this chemical get out of balance, so do sleep patterns.” In this study, 65 percent of the patients receiving hydroxyzine before bedtime experienced improved sleep quality.

Dr. Spahr says that hydroxyzine is a welcome alternative to ‘classical’ sleeping pills, as they are usually ineffective and can lead to serious side effects in cirrhosis patients, such as coma. Recent practice guidelines forbid the use of these ‘classical’ drugs for cirrhosis patients, declaring them too dangerous.

According to Dr. Spahr, however, hydroxyzine is not risk-free. “This medication must be used with caution. Patients must be monitored carefully by a physician for their particular response to the drug, and should be taken off the medication if there are any signs of trouble.”


Story Source:

The above story is based on materials provided by Blackwell Publishing. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing. "Antihistamine Offers Relief For Cirrhosis Patients With Insomnia." ScienceDaily. ScienceDaily, 28 May 2007. <www.sciencedaily.com/releases/2007/05/070527100414.htm>.
Blackwell Publishing. (2007, May 28). Antihistamine Offers Relief For Cirrhosis Patients With Insomnia. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2007/05/070527100414.htm
Blackwell Publishing. "Antihistamine Offers Relief For Cirrhosis Patients With Insomnia." ScienceDaily. www.sciencedaily.com/releases/2007/05/070527100414.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins