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Endocrine Researchers To Discuss Gene That May Be Linked To Polycystic Ovary Syndrome

Date:
June 2, 2007
Source:
Cedars-Sinai Medical Center
Summary:
Researchers will discuss a gene that appears to play a role in the development of polycystic ovary syndrome, the most common endocrine disorder among reproductive-age women, at upcoming meetings.

Researchers in endocrinology and obstetrics and gynecology at Cedars-Sinai Medical Center will discuss a gene that appears to play a role in the development of polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women, at upcoming meetings.

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Women with PCOS have many small cysts on the periphery of the ovaries and suffer from symptoms that include menstrual irregularities, excess weight, skin problems and an excess of male-type hair growth called hirsutism. These women also are often found to have insulin resistance, a condition that allows high levels of insulin to circulate in the blood, which increases risk of developing type 2 diabetes, hypertension and heart disease.

PCOS also is associated with excessive levels of androgens -- "male" hormones that normally exist at low levels in women. The effects on androgen production by hormones secreted by fat tissue (adipokines) are being studied at Cedars-Sinai, and several researchers will present related findings at the meetings. Researchers also will present preliminary evidence that the level of androgens produced by the adrenal glands of pre-adolescent girls may serve as markers of the risk of PCOS.

Ricardo Azziz, M.D., chairman of Cedars-Sinai's Department of Obstetrics and Gynecology, will open the Androgen Excess Society meeting with a brief history of the study of androgen excess disorders. The Androgen Excess Society meets June 1. The Endocrine Society meeting extends from June 2 through 5. Both will be held in Toronto, Canada.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Endocrine Researchers To Discuss Gene That May Be Linked To Polycystic Ovary Syndrome." ScienceDaily. ScienceDaily, 2 June 2007. <www.sciencedaily.com/releases/2007/06/070601103846.htm>.
Cedars-Sinai Medical Center. (2007, June 2). Endocrine Researchers To Discuss Gene That May Be Linked To Polycystic Ovary Syndrome. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2007/06/070601103846.htm
Cedars-Sinai Medical Center. "Endocrine Researchers To Discuss Gene That May Be Linked To Polycystic Ovary Syndrome." ScienceDaily. www.sciencedaily.com/releases/2007/06/070601103846.htm (accessed October 25, 2014).

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