Featured Research

from universities, journals, and other organizations

Include Children In Research To Make Breakthroughs In Child Medicine, Says Expert

Date:
July 9, 2007
Source:
Imperial College London
Summary:
Scientists will only make real breakthroughs in children's medicine if they include children in research programmes as well as adults, according to a leading paediatric expert. The first studies to be conducted by the new Paediatric Research Unit will be a trial looking at preventing allergies using prebiotics in high risk infants; a unique treatment for Duchenne dystrophy, which has hitherto been incurable; a study looking at the use of a helium oxygen mixture in intensive care and to treat acute bronchiolitis; and studies into the impact of various allergic problems on sleep and daytime behaviour.

Scientists will only make real breakthroughs in children's medicine if they include children in research programmes as well as adults, according to a leading paediatric expert.

Professor John Warner was speaking recently at the opening of the Paediatric Research Unit, the UK's first unit solely devoted to paediatric clinical research. The unit is run by researchers from Imperial College London and St Mary's Hospital, and it is based next to the hospital's paediatric wards in Paddington.

Professor Warner, who is Chair in Paediatrics and Head of the Department of Paediatrics at Imperial College and consultant paediatrician at St Mary's Hospital, explained that researchers should be designing therapies specifically for children and their problems, rather than scaling down treatments that were created for adults. In many respects the makeup of children differs from that of adults: they have different metabolisms; their organs are not as mature as adults'; and diseases can behave differently in children's bodies.

"To create the best therapies for children we need to include them in our research," said Professor Warner. "A lot of paediatricians' work doesn't have much of a scientific evidence base and we prescribe drugs by extrapolating from what we know about adult bodies. We have a desperate need to understand precisely how children's bodies work so that we can custom-design therapies for them and their problems."

Researchers in the new unit will be investigating many areas including paediatric allergies and how these can be prevented; sleep disturbance and how this affects health and behaviour; new treatments for acute and chronic chest disorders such as bronchiolitis and asthma. They will also be looking at infectious diseases and immunisation; new treatments for neuromuscular diseases such as Duchenne muscular dystrophy; and prevention of the complications of sickle cell disease, to name but a few.

Professor Warner said that people should be assured that all research involving children would be carried out ethically and responsibly.

"We will of course be operating to the highest ethical standards and we will go to great lengths to ensure the safety of all the children in our care. If you think something might help children but you're not certain, it is unethical not to do the research and find out. You might be depriving a child of something that could do immense good," explained Professor Warner.

The new 650,000 unit includes two outpatient consulting rooms and two ensuite inpatient rooms, with enough space for a child and their parent to sleep in and with a monitoring room between. It also has a large waiting and play area, a lung function investigation room, a laboratory, offices for staff, a reception and a treatment room.

The first studies to be conducted by the unit will be a trial looking at preventing allergies using prebiotics in high risk infants; a unique treatment for Duchenne dystrophy, which has hitherto been incurable; a study looking at the use of a helium oxygen mixture in intensive care and to treat acute bronchiolitis; and studies into the impact of various allergic problems on sleep and daytime behaviour.


Story Source:

The above story is based on materials provided by Imperial College London. Note: Materials may be edited for content and length.


Cite This Page:

Imperial College London. "Include Children In Research To Make Breakthroughs In Child Medicine, Says Expert." ScienceDaily. ScienceDaily, 9 July 2007. <www.sciencedaily.com/releases/2007/07/070708193014.htm>.
Imperial College London. (2007, July 9). Include Children In Research To Make Breakthroughs In Child Medicine, Says Expert. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2007/07/070708193014.htm
Imperial College London. "Include Children In Research To Make Breakthroughs In Child Medicine, Says Expert." ScienceDaily. www.sciencedaily.com/releases/2007/07/070708193014.htm (accessed April 23, 2014).

Share This



More Mind & Brain News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
Do We Get Nicer With Age?

Do We Get Nicer With Age?

Newsy (Apr. 22, 2014) A recent report claims personality can change over time as we age, and usually that means becoming nicer and more emotionally stable. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com
Sorry, Guys, Only Women Can Make Their Voices Sound Sexier

Sorry, Guys, Only Women Can Make Their Voices Sound Sexier

Newsy (Apr. 21, 2014) According to researchers at Albright College, women have the ability to make their voices sound sexier, but men don't. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins