Featured Research

from universities, journals, and other organizations

Layered Approach May Yield Stronger, More Successful Bone Implants

Date:
August 22, 2007
Source:
National Institute of Standards and Technology
Summary:
Researchers have developed a new method for layering two kinds of biomaterials into one strong, yet porous unit that may lead to improved reconstruction or repair of bones.

High-magnification scanning electron microscopy shows (center of micrograph) the leg of an osteoblast (bone precursor), called a cytoplasmic extension, attaching to nano-sized hydroxyapatite crystals, similar to those in natural bone, that make up a CPC implant.
Credit: NIST

Researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST) have developed a new method for layering two kinds of biomaterials into one strong, yet porous unit that may lead to improved reconstruction or repair of bones.

Currently, calcium phosphate cements (CPCs)--water-based pastes of powdered calcium and a phosphate compound that form hydroxyapatite, a material found in natural bone--are used for reconstructing or repairing skeletal defects, but only in bones that are not load-bearing (such as those in the face and skull). Macropores built into the CPCs make it easier for new bone cells to infuse and, eventually, solidify the implant. Until this happens, however, the macropores leave the implant brittle and susceptible to failure.

In the September 2007 issue of Biomaterials,* Hockin Xu and colleagues describe a unique approach for providing the strength needed to help an implant better survive its early stages. First, a macroporous CPC paste is placed into the area needing reconstruction or repair. Then, a strong, fiber-reinforced CPC paste is layered onto the first CPC to support the new implant.

Once new bone has grown into the macroporous layer and increased its strength, the absorbable fibers in the strong layer dissolve and create additional macroporous channels that promote even more bone tissue ingrowth. This method mimics the natural bone structure in which a strong layer, called cortical bone, covers and strengthens a weaker, macroporous layer (spongy bone).

The two pastes used in the layered CPC method harden in the bone cavity to form an implant that for the first time has both the porosity needed for bone growth and the integrity required for reconstruction or repair of load-bearing bones (such as jaws).

NIST and the ADAF have conducted cooperative research on dental and medical materials since 1928. ADAF researchers focus on development of new dental and biomedical materials, while NIST specializes in the development of improved technologies and methods for measuring materials properties.

The research was funded by the U.S. Public Health Service, NIST and ADAF.

* H.K. Xu, E.F. Burguera and L.E. Carey. Strong, macroporous, and in situ-setting calcium phosphate cement-layered structures. Biomaterials 28 (September 2007), pp. 3786-3796.


Story Source:

The above story is based on materials provided by National Institute of Standards and Technology. Note: Materials may be edited for content and length.


Cite This Page:

National Institute of Standards and Technology. "Layered Approach May Yield Stronger, More Successful Bone Implants." ScienceDaily. ScienceDaily, 22 August 2007. <www.sciencedaily.com/releases/2007/08/070817102008.htm>.
National Institute of Standards and Technology. (2007, August 22). Layered Approach May Yield Stronger, More Successful Bone Implants. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2007/08/070817102008.htm
National Institute of Standards and Technology. "Layered Approach May Yield Stronger, More Successful Bone Implants." ScienceDaily. www.sciencedaily.com/releases/2007/08/070817102008.htm (accessed September 3, 2014).

Share This



More Health & Medicine News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins