Featured Research

from universities, journals, and other organizations

Designing Better Markers For Pregnancy-associated Pathological Conditions

Date:
August 26, 2007
Source:
American Society for Biochemistry and Molecular Biology
Summary:
Researchers report the most complete list so far of proteins present in the human amniotic fluid, the liquid that surrounds a fetus during pregnancy. The new information may be used to develop new or improved markers of pregnancy-associated pathological conditions, such as preterm delivery, intra-amniotic infection, and chromosomal anomalies in the fetus.

Researchers report the most complete list so far of proteins present in the human amniotic fluid, the liquid that surrounds a fetus during pregnancy. The new information may be used to develop new or improved markers of pregnancy-associated pathological conditions, such as preterm delivery, intra-amniotic infection, and chromosomal anomalies in the fetus.

The amniotic fluid is initially formed from maternal plasma that later crosses fetal membranes from 10 to 20 weeks of gestation. By looking at the composition of the amniotic fluid in this gestational stage, scientists can provide valuable information about the health of the fetus and may indicate potential pathological conditions. Although many amniotic fluid proteins are known and are currently used to detect potential fetal anomalies, little is known about the functions of these proteins and how they interact with one another.

Eleftherios P. Diamandis and colleagues showed that the amniotic fluid contains at least 850 proteins, many of which have not been discovered before and that could be used as new markers for genetic defects or pathological conditions in the fetus. Current markers used for that purpose either do not detect defects in all affected fetuses -- leaving some mothers with a negative diagnosis while their baby actually has a defect -- or incorrectly diagnose some fetuses as having a defect when no such defect exists. Also, although they reveal defects, these markers cannot pinpoint the origin of the defect. The newly identified proteins could help design markers that are easier to detect and provide more details about potential defects.

Article: "Proteomic Analysis of Human Amniotic Fluid," by Chan-Kyung J. Cho, Shannon J. Shan, Elizabeth Winsor, and Eleftherios P. Diamandis


Story Source:

The above story is based on materials provided by American Society for Biochemistry and Molecular Biology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Biochemistry and Molecular Biology. "Designing Better Markers For Pregnancy-associated Pathological Conditions." ScienceDaily. ScienceDaily, 26 August 2007. <www.sciencedaily.com/releases/2007/08/070823111923.htm>.
American Society for Biochemistry and Molecular Biology. (2007, August 26). Designing Better Markers For Pregnancy-associated Pathological Conditions. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2007/08/070823111923.htm
American Society for Biochemistry and Molecular Biology. "Designing Better Markers For Pregnancy-associated Pathological Conditions." ScienceDaily. www.sciencedaily.com/releases/2007/08/070823111923.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins