Featured Research

from universities, journals, and other organizations

Being Overweight May Independently Increase Risk For Heart Disease

Date:
September 16, 2007
Source:
JAMA and Archives Journals
Summary:
Being moderately overweight or obese appears to increase the risk for developing coronary heart disease events independent of traditional cardiovascular risk factors, according to a meta-analysis of previously published studies.

Being moderately overweight or obese appears to increase the risk for developing coronary heart disease events independent of traditional cardiovascular risk factors, according to a meta-analysis of previously published studies in the September 10 issue of Archives of Internal Medicine.

Nearly two-thirds of U.S. adults are overweight and therefore at higher risk for heart disease, other illnesses and death, according to background information in the article. "Because of the high prevalence of overweight and the expected future increases, it is essential to gain precise insight into the consequences of overweight for health and into the metabolic pathways that link the two," the authors write.

Rik P. Bogers, Ph.D., of the Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, the Netherlands, and colleagues combined data from 21 previous studies of overweight and heart disease that included a total of 302,296 participants.

A total of 18,000 heart events or deaths occurred among these participants during the studies. After the researchers factored in age, sex, physical activity levels and smoking, moderately overweight individuals had a 32 percent increased risk of heart disease compared those who were not overweight. Obesity increased their risk 81 percent over those of normal weight.

The researchers then adjusted the figures further for blood pressure and cholesterol levels. This reduced the excess risk associated with being moderately overweight by 47 percent, to 17 percent, and with obesity by 40 percent, to 49 percent. For every five units an individual's body mass index increased, the risk for heart disease increased 29 percent before adjusting for blood pressure and cholesterol and 16 percent after adjustment.

"Hence, the present study indicates that adverse effects of overweight on blood pressure and cholesterol levels could account for about 45 percent of the increased risk of coronary heart disease, and that there is still a significantly increased risk of coronary heart disease that is independent of these effects," the authors write. "This implies that, even under the theoretical scenario that optimal treatment would be available against hypertension and hypercholesterolemia in overweight persons, they would still have an elevated risk of coronary heart disease."

They propose several other mechanisms by which being overweight could increase the risk of heart disease, including constant low-grade inflammation, problems with blood vessel function or an imbalance in blood chemicals that could lead to more clotting.

Reference: Arch Intern Med. 2007;167(16)1720-1728.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Being Overweight May Independently Increase Risk For Heart Disease." ScienceDaily. ScienceDaily, 16 September 2007. <www.sciencedaily.com/releases/2007/09/070910162400.htm>.
JAMA and Archives Journals. (2007, September 16). Being Overweight May Independently Increase Risk For Heart Disease. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2007/09/070910162400.htm
JAMA and Archives Journals. "Being Overweight May Independently Increase Risk For Heart Disease." ScienceDaily. www.sciencedaily.com/releases/2007/09/070910162400.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins